摘要
目的比较不同术式对重型颅脑损伤患者血小板活化指标及脑血管痉挛状态的影响。方法选取2011-02—2012-07于本院进行小骨窗开颅手术治疗的34例重型颅脑损伤患者为A组,另将同时期采用标准大骨瓣开颅手术进行治疗的34例患者为B组,然后将2组患者手术后不同时间的GOS评分及手术前后的血小板活化指标及脑血管痉挛状态指标进行比较。结果 B组手术后3个月、6个月的GOS评分均明显优于A组,术后1d、3d、7d的血管痉挛总发生率均低于A组,血小板活化指标也均低于A组,P值均<0.05,差异有统计学意义。结论标准大骨瓣开颅手术救治中,更有助于改善患者的血小板活化指标及脑血管痉挛状态的效果较好。
Objective To compare the influence of different operation methods on the platelet activation indexes and cerebral vasospasm state of patients with severe craniocerebral injury.Methods 34 patients with severe craniocerebral injury treated with small bone window craniotomy operation in our hospital from February 2011 to July 2012 were considered as the group A,and 34 cases treated with standard large trauma craniotomy with bone flap operation at the same period were considered as the group B.We also compared the GOS score after operation at different times as well as platelet activation indexeds and cerebral vasospasm state before and after the operation of two groups.Results The GOS score of group B after operation at 3th and 6th month were obviously better than that of group A（P0.05）;Ccerebral vasospasm indexes and rate of group B after operation at 1st,3rd and 7th day were lower than these of group A（P0.05）,and platelet activation indexes of group B were also lower than these of group A（P0.05）.Conclusion The effect of standard large trauma craniotomy with bone flap operation in patients with severe craniocerebral injury is better,which is benefit for the improvement of platelet activation markers and cerebral vasospasm state.
出处
《中国实用神经疾病杂志》
2013年第13期13-15,共3页
Chinese Journal of Practical Nervous Diseases
关键词
重型颅脑损伤
血小板活化
脑血管痉挛
Severe craniocerebral injury
Platelet activation
Cerebral vasospasm
