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电针刺足三里、曲池对自发性高血压大鼠血压影响与培哚普利等效性随机平行对照研究 被引量:9

Electroacupuncture Zusanli,Quchi Controlled Study on the Effect on Blood Pressure of Spontaneously Hypertensive Rats with Perindopril Equivalent Random Parallel
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摘要 [目的]观察电针刺足三里、曲池对自发性高血压大鼠血压影响。[方法]使用随机平行对照方法,将30只雄性自发性高血压京都种大鼠编号按(随机数字表)方法随机分为3组,10只/组;同龄同系正常血压京都种大鼠10只。各组均捆绑束缚20min(自制固定架将四肢固定),1次/d。高血压蒸馏水组(SHR)、培哚普利组(0.4mg/kg.d)、正常组(WKY)组连续灌胃6周;针灸治疗组取双侧曲池和足三里电针刺激,以大鼠肢体微微颤动为度(1~2mA),疏密波,20min/次,1次/d,连续针刺6d,休息1d,连续针刺6周。观测指标大鼠尾动脉收缩压。[结果]尾动脉压收缩压,干预前与正常组比较,各组大鼠收缩压均较高。干预6周后,培哚普利组、电针组收缩压明显降低,组间无明显差异(P>0.05);与蒸馏水组比较,均显著降低(P<0.05)。[结论]电针刺足三里、曲池对原发性高血压大鼠血压影响与培哚普力具有等效性。相似的理想效果。 [Objective]To observe the effect of electroacupuncture at Zusanli,Quchi effect on blood pressure in spontaneously hypertensive rats.[Methods]Randomized controlled method,30 male spontaneously hypertensive Kyoto rats No.(random number table) were randomly divided into 3 groups of 10 mice/group;Kyoto rats of the same age and normal blood pressure of 10.Each group were bundled bound 20min(homemade holder limbs fixed),once/day.Hypertension distilled water group(SHR),perindopril group(0.4mg/kg.d),the normal group(WKY) group intragastric administration of 6 weeks;acupuncture treatment group were the bilateral Quchi and Zusanli electroacupuncture,rat limbs quivering for the degree(2mA),density wave,20min /,once/day,continuous acupuncture 6 days rest 1 day acupuncture 6 consecutive weeks.Observations rat tail artery systolic blood pressure.[Results]Tail artery pressure systolic blood pressure before intervention compared with normal group,the rats systolic blood pressure is higher.After 6 weeks of intervention,the perindopril group,EA group systolic blood pressure was significantly lower,no significant difference(P0.05) between the two groups;compared with the distilled water group,were significantly lower(P0.05).[Conclusion]The effect of electroacupuncture Zusanli,Qu pool Spontaneously Hypertensive Rats effect on blood pressure with perindopril Cape of equivalence.Similar desired effect.
出处 《实用中医内科杂志》 2013年第4期64-65,共2页 Journal of Practical Traditional Chinese Internal Medicine
关键词 自发性高血压大鼠 针刺 足三里 曲池 培哚普利 等效性随机平行对照研究 Spontaneously hypertensive rats Acupuncture Zusanli Quchi Perindopril Equivalence randomized controlled study
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