摘要
目的观察认知行为疗法在治疗非糜烂性反流病合并疑病症患者的临床疗效。方法将42例非糜烂性反流病合并疑病症患者随机分为治疗组21例和对照组21例,对照组采用雷贝拉唑10mg,po,bid、多潘立酮10mg,po,tid治疗(常规治疗),治疗组在对照组治疗的基础上,实施认知行为疗法治疗,两组疗程均为8周,比较两组治疗后症状缓解、RDQ问卷评分、症状自评量表(SCL-90)评分及明尼苏达多项人格测验(MMPI)改善情况。结果经治疗8周后,对照组中显效28.6%,总有效率47.6%;治疗组中显效61.9%,总有效率85.7%,两组总有效率差异有显著性(P<0.05);治疗前,治疗组与对照组在RDQ问卷评分、SCL-90评分及MMPI评分方面相比差异均无显著性(P>0.05),其中SCL-90评分有3个因子>2分,包括强迫、焦虑、抑郁因子,提示患者处于强迫、焦虑、抑郁状态,但从病情程度来看,未达强迫症、焦虑神经症、抑郁神经症诊断参照标准;经治疗8周后,治疗组与对照组在RDQ问卷评分、SCL-90评分及MMPI评分的T分,如疑病、抑郁、癔症、精神病态、偏执、精神衰弱方面相比差异有显著性,具有统计学意义(P<0.05)。结论认知行为疗法可以显著改善非糜烂性反流病合并疑病症患者的胃食管反流症状,同时明显改善患者疑病、焦虑、抑郁等心理障碍,明显提高患者生活质量,值得临床推广。
Objective To observe the clinical effectiveness of the cognitive behavioral therapy （CBT） in the treatment of patients with non-erosive reflux disease （NERD） combined hypochondriasis. Methods Forty two patients with NERD combined with hypochondriasis were randomly assigned into two groups： treatment group （n=21）and control group（n=21）. Patients in control group were treated with rabeprazole（10 mg po. bid）, domperidone（10 mg po.tid）（conventional treatment）. While patients in treatment group was added with （CBT） . The treatment period was eight weeks. The symptom scale, reflux diagnostic questionnare （RDQ） scale , SCL-90 scale, and MMPI scale were compared. Results After 8-week treatment,there were significant differences between the two groups on main symptoms, with total effective rate of 85.7% in treatment group and 47.6% in control group （P0.05）. There were no significant difference between the two groups on RDQ scores, SCL-90 score and MMPI score before treatment （P0.05）. However, after 8-week treatment, there were significant differences between the two groups on RDQ scores, SCL-90 score, and T points of MMPI such as hypochondria, depression, hysteria, psychopathic deviate, paranoia and psychasthenia（P0.05）. Conclusion CBT could significantly improve the gastroesophageal reflux symptoms of patients with NERD combined with hypochondriasis, and at the same time could significantly improve the mood disorder of patients.
出处
《现代消化及介入诊疗》
2013年第3期148-151,共4页
Modern Interventional Diagnosis and Treatment in Gastroenterology
关键词
认知行为疗法
非糜烂性反流病
疑病症
雷贝拉唑
Cognitive behavioral therapy
Non-erosive reflux disease
Hypochondriasis
Rabeprazole
