摘要
射频消融（radiofrequency ablation，RFA）已广泛应用于因多种原因不能手术切除的肝细胞癌（hepatocel—lularcarcinoma，HCC）患者的治疗，且对于能达到肿瘤“一次性”（one—off）完全消融的患者其疗效不逊于外科手术。然而，由于现有热消融技术的局限性，肿瘤大小及所处部位的特殊性，临床医生有时无法实施“一次性”完全消融。而不完全的和多次重复的RFA是影响患者预后的重要因素之一。为达到“一次性”完全消融目的，术前准确评估肝脏肿瘤的解剖学位置，选择不同的RFA治疗方法和步骤非常重要。本文依据肝脏解剖学特征，结合肝胆外科的专业优势，系统分析探讨了肿瘤“一次性”完全消融的理论基础和安全实施策略。
The technique of Radiofrequency ablation （RFA） has been widely applied as alternative treatment for non-resectable hepatocellular carcinoma （HCC） and has e- quivalent efficacy in prognosis. However, because of the re- striction of current heat ablation technique and tumor＇s ＂spe- cial location＂ in liver, it is difficult for some physicians to obtain the ideal of ＂one-off＂ complete ablation. Therefore, incomplete destruction of tumor and multiple ablation proces ses resulted in miserable consequence in prognosis. So, to a- chieve ＂one-off＂ complete ablation, it is essential to evaluate the anatomy location of the tumor before RFA procedure and to establish the specified approach and adjuvant method. This article is to systematically analyze the theoretical hy- pothesis of this technique and to explore possible strategy for a safe approach based on characteristics of liver anatomy and combined with the professional advantages of hepatobiliary surgery.
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2013年第7期487-490,共4页
Chinese Journal of Hepatobiliary Surgery
基金
国家科技部支撑计划项目（2012BA106801）
关键词
肝肿瘤
射频消融
一次性
理论
治
疗效果
Liver neoplasm
Radiofrequency abla- tion, one-off
Theory
Treatment effectiveness
