摘要
目的研究血清孕酮(P)和β-绒毛膜促性腺激素(β-HCG)联合检测在早期先兆流产中的临床应用价值,为早期先兆流产的诊断提供理论依据。方法对32例先兆流产患者,44例流产患者和30例健康对照组的血清孕酮及β-HCG进行检测。结果流产组两项指标均明显低于先兆流产组和对照组,差异具有统计学意义(P<0.01);先兆流产组患者两项指标均明显低于对照组,差异具有统计学意义(P<0.01);发现流产组患者P<30 ng/ml和β-HCG<5000 mIU/ml的比例明显高于继续妊娠组的比例,差异有统计学意义(P<0.05),并且孕酮和β-HCG联合检验对妊娠结局的敏感性为88.32%,特异性为93.44%。结论血清孕酮和β-HCG联合检测能明显提高对早期先兆流产的预测率。
Objective To study clinical application value of combined detection of the serum progesterone and β-HCG in the diagnosis of early threatened abortion, and to provide a theoretical basis. Methods 32 cases of threatened abortion patients ,44 cases of abortion patients and 30 healthy controls were enrolled, the serum progesterone and β-HCG were detected. Results The two indicators in abortion group were significantly lower than those of threatened abortion group and control group, the difference was statistically significant（ P 〈 0.01 ） ,two indexes in threatened abortion patients were lower than those in the control group ,the difference was statistically significant（P 〈 0.01 ）, it was found that P 〈 30 ng/ml and [3-HCG 〈 5000 mIU/ml ratio in abortion group was significantly higher than that of the continuing pregnancy group, difference had statistical significance （P 〈 0.05 ） , the sensitivity and the specificity of the joint determination of β-HCG and progesterone in prediction of pregnancy outcome were 88.32% and 93.44%, respectively. Conclusion The combined detection of serum progesterone and β-HCG can significantly improve the prediction of early threatened abortion.
出处
《中华全科医学》
2013年第9期1389-1390,共2页
Chinese Journal of General Practice
关键词
孕酮
Β-HCG
先兆流产
Progesterone
β-HCG
Threatened abortion
