摘要
目的:观察和探讨头颅局部亚低温联合血塞通治疗急性脑梗死的临床疗效。方法:将2010年5月-2011年12月我院收治的急性脑梗死患者86例,随机分为对照组(43例)和治疗组(43例)。对照组仅用常规药物治疗,治疗组在常规治疗的基础上加用头颅局部亚低温联合血塞通,连续治疗10天,观察其对急性脑梗死患者神经功能缺损的治疗作用,及治疗前后血浆神经元特异性烯醇化酶(NSE)的变化。结果:神经功能使用欧洲卒中量表(ESS)进行评价,对照组治疗后ESS评分较治疗前提高(P<0.05),但治疗组提高更为明显(P<0.01);对照组治疗后血浆NSE水平较治疗前降低(P<0.05),而治疗组降低更为明显(P<0.01)。结论:临床上治疗急性脑梗死,联合头颅局部亚低温及血塞通比单纯常规治疗的效果更好,可有效改善患者的神经功能缺损及生活质量。
Objective：To evaluate the curative effect of the treatment of acute cerebral infarction with local hypothermia of heads combined Xuesaitong injection. Methods：76 cases of acute cerebral infarction patients from May 2010 to June 2011 ,were randomly divided into control group （38 cases）and trial group （38 cases）. control group are only treated with conventional drugs while trial group are treated with local hypothermia of heads combined Xuesaitong injection on the basis of conventional therapy for 10 days in a row. observe the treatment effect of local hypothermia combined with Xuesaitong injection on nerve function defect and the specificity of neurons plasma enolization enzyme before and after treatment . Results：By using the European stroke scale （ESS）to assess the neural function , we know that ESS scores of the two groups after treatment are higher than that before treatment （P0.05）,but the trial group improved a lot more than the control group （P0.01）. Serum NSE levels of the two groups after treatment were reduced on average （P0.05）,while the trial group decreased a bit more than the control group （P 0.01）. Conclusion：We draw the conclusion that the clinical treatment of acute cerebral infarctionwith local hypothermia of heads combined Xuesaitong injection is better than that of conventional treatment alone,which can effectively improve neural function defect and the quality of life of patients.
出处
《甘肃医药》
2013年第7期503-505,共3页
Gansu Medical Journal
关键词
头颅局部亚低温
血塞通
联合治疗
急性脑梗死
临床观察
heads of local hypothermia
Xuesaitong injecion
combination therapy
acute cerebral infarction
clinical observation
