摘要
目的了解深圳市龙岗区重症手足口病的流行特征并探讨其重症发病的危险因素。方法回顾性收集2009-2012年深圳市龙岗区重症手足口病发病资料进行描述性分析,同时收集82例重症和106例普通手足口病的个案调查信息,采用Logistic回归分析进行重症手足口病发病相关危险因素分析。结果深圳市龙岗区重症手足口病发病率为0.70/10万,发病高峰为5-7月,散居儿童的重症比例(101/31 394)显著高于其他人群(7/9 391)(χ2=16.723,P=0.000);重症病例发病主要集中在1岁(中位数),与普通病例(中位数2.7岁)相比,重症发病年龄显著偏低(t=3.127,P=0.002)。多因素Logistic回归分析显示,在排除其他因素的影响后,血常规检测白细胞计数高(OR=1.598,P=0.003)、发热持续时间长(OR=6.186,P=0.035)是重症手足口病发病的危险因素。结论龙岗区重症病例以1岁儿童发病为主,散居儿童居多,夏季高发,白细胞计数上升、发热持续时间长为重症手足口病的危险因素,在医疗机构中开展相关的早期监测对防止重症死亡病例的发生具有非常重要的意义。
Objective To understand the epidemiological characteristics of severe cases of hand foot mouth disease（HFMD）in Longgang district and explore its influencing factors.Methods Data of severe HFMD cases in Longgang district from 2009 to 2012 were retrospectively collected for descriptive analysis.Case investigation data of 82 severe cases and 106 common cases were collected for logistic regression analysis.Results The incidence rate of severe HFMD cases in Longgang district from 2009 to 2012 was 7.0 per million.The reported peak time of incidence of severe HFMD cases appeared in May to July.The proportion of severe cases among scattered children was significantly higher than those among other populations（χ^2=16.723,P=0.000）.The median age of the severe cases was 1 year old,which was significantly lower than that of the common cases（t=3.127,P=0.002）.Multiple factor logistic regression analysis indicated that high white blood count（OR=1.598,P=0.003）and long fever duration（OR=6.186,P=0.035） were independent risk factors for severe cases of hand foot mouth disease.Conclusions The severe cases of hand foot mouth disease in Longgang District of Shenzhen mainly occur in children aged 1 year old and among scattered children.Summer is the epidemical season.High white blood count and long fever duration are risk factors for severe cases.Monitoring the risk factors in medical services plays an important role to prevent the death due to hand foot mouth disease.
出处
《实用预防医学》
CAS
2013年第7期789-791,共3页
Practical Preventive Medicine
基金
深圳市龙岗区医疗卫生科研项目(YS2012034)
关键词
手足口病
重症病例
流行特征
危险因素
Hand foot mouth disease
Severe cases
Epidemiological characteristics
Risk factors
