摘要
目的研究分析中心静脉导管相关性血流感染(CLABSI)的临床特征,为预防与控制CLABSI提供临床依据。方法采用回顾性调查方法对2009-2011年CLABSI资料汇总进行统计分析。结果 600例住院患者发生CLABSI53例,发病率为7.1‰;在分离出的53株病原菌中以革兰阳性球菌为主,共27株占50.94%,真菌14株占26.42%,革兰阴性杆菌12株占22.64%;CLABSI发病率与插管时间、插管部位、导管腔数、全胃肠外营养(TPN)有关,差异有统计学意义(P<0.05),CLABSI发病率与最大无菌屏障及灌注抗菌药物无关(P>0.05)。结论插管时间、插管部位、导管腔数、全胃肠外营养是CLABSI的主要因素,应针对上述因素制定相应的干预措施,以降低CLABSI的发生。
OBJECTIVE To investigate and analyze the clinic features of central venous catheter-related infections so as to provide basis for the prevention and control of catheter-related bloodstream infections.METHODS By means of the retrospective survey,the data of the patients with central venous catheter-related infections who were hospitalized during 2009-2011 were statistically analyzed.RESULTS Of totally 600 cases of hospitalized patients,the central venous catheter-related infections occurred in 53 cases with the incidence rate of 7.1‰.There were totally 53 strains of pathogens isolated,including 27（50.94%）strains of gram-positive bacteria,14（26.42%） strains of fungi,and 12（22.64%）strains of gram-negative bacilli.The incidence of central venous catheterrelated infections was related to the catheterization duration,intubation site,number of catheter lumen,and total parenteral nutrition（TPN）,and the difference was significant（P0.05）;the incidence of central venous catheter-related infections was not related to the maximum sterile barrier or the perfusion of antibiotics（P0.05）.CONCLUSIONThe catheterization duration,intubation site,number of catheter lumen,and TPN are the main risk factors of the central venous catheter-related infections;it is necessary to formulate the corresponding interventions according to the risk factors so as to reduce the incidence of central venous catheter-related infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第14期3366-3368,共3页
Chinese Journal of Nosocomiology
基金
河北省科技计划项目(12277723)
