摘要
帕金森病是一种中老年人常见的中枢神经系统变性疾病,其症状表现为震颤,肌强直、运动迟缓以及姿势平衡障碍等。目前的研究已经证明了维生素D与帕金森病存在显著关联,维生素D可能对帕金森病患者提供保护作用,维生素D水平较高的人群患帕金森病的风险相对较低。帕金森病患者中的血清25-(OH)D3水平较低,骨密度降低及骨质疏松症非常普遍,这为帕金森病的治疗提供了一个新的靶点。
Parkinson disease（PD） is the most common neurodegeneration in the elderly population.It is characterized by tremor,rigidity,slowness of movement,and postural imbalance.A significant association between serum vitamin D and PD has been demonstrated,vitamin D might provide protection against PD.Individuals with higher serum vitamin D concentrations showed a reduced risk of PD.Low 25-（OH） D3 level,reduced bone mass and osteoporosis are very common in PD patients,which may provide a new target for the treatment of PD.
出处
《医学综述》
2013年第13期2330-2333,共4页
Medical Recapitulate
