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系统性红斑狼疮并化脓性脑膜炎误诊为狼疮性脑病

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摘要 目的探讨系统性红斑狼疮(systemic lupus erythematosus,SLE)合并化脓性脑膜炎(化脑)的临床特点,以减少误诊误治。方法回顾性分析1例误诊为狼疮性脑病的SLE合并化脑的临床资料,并复习相关文献。结果患者有SLE病史6年,目前以泼尼松5 mg/d维持治疗。因发热、双下肢散在皮疹3 d入院,查血清炎性指标偏高,狼疮活动指标正常。病程中出现头痛伴高热,考虑狼疮性脑病予大剂量糖皮质激素治疗后症状不缓解,行腰椎穿刺(腰穿)脑脊液检查提示化脑,经长时间抗感染治疗后症状好转。结论当SLE患者出现中枢神经系统(CNS)症状时,应想到合并CNS感染可能,及时行腰穿脑脊液病原学检查,以明确感染性质,减少误诊。
出处 《临床误诊误治》 2013年第7期34-36,共3页 Clinical Misdiagnosis & Mistherapy
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