摘要
目的:评价感染性休克患者每搏量变异对于预测容量反应性的准确性。方法:16例外科感染性休克的患者,进行容量负荷试验。分别于扩容前后记录患者心率(heart rate,HR)、中心静脉压(central venous pressure,CVP)、平均动脉压(mean arterial pressure,MAP)、每搏量变异(stroke volume variation,SVV)以及每搏量指数(stroke volume index,SVI)。容量反应性阳性定义为容量负荷后患者SVI增加不少于10%。结果:16例患者中,12例患者为容量反应性阳性,4例为容量反应性阴性。容量负荷后所有患者CVP以及SVI显著增加(P均<0.01),而SVV显著降低(P均<0.01)。容量反应性阳性的患者,其容量负荷前的SVV明显高于容量反应性阴性的患者(P<0.01)。以SVV=12.5%为界值,其判断容量反应性的灵敏度为80%,特异度为100%。结论:SVV能准确地预测感染性患者的容量反应性。
Objective： To evaluate fluid responsiveness by stroke volume variation（SVV） in patients with septic shock.Methods： 16 septic shock patients were enrolled in the study.According to the responsiveness of fluid loading,the patients were divided into responsive group（n=12） and nonresponsive group（n=4）.The SVV values of two groups were retrospectively analyzed.The receiver operating characteristic curve was drafted to determine the cut-off value of SVV for predicting fluid responsiveness.Results： Among the 16 septic shock patients,12 were responsive to fluid loading,4 were not;before the fluid loading,central venous pressure,heart rate and mean arterial pressure in both groups showed no significant difference whereas SVV in the responsive group was much higher than that in the nonresponsive group（P0.01）.Using the threshold of SVV≥12.5% to predict fluid responsiveness,the sensitivity was 80%,specificity was 100%.Conclusion： SVV accurately predict fluid responsiveness in septic shock patients.
出处
《现代生物医学进展》
CAS
2013年第21期4122-4124,4098,共4页
Progress in Modern Biomedicine
关键词
每搏量变异
感染性休克
容量反应性
Stroke volume variation
Septic shock
Fluid responsiveness
