期刊文献+

乳腺癌148例临床病理分析

原文传递
导出
摘要 目的了解本地区乳腺癌的临床病理特点。方法回顾性分析148例乳腺癌的临床及病理特点,对c-erbB-2的表达与ER、PR及临床病理因素的相关性进行分析。结果 148例中女性占99.3%(147例),发病平均年龄49.2岁,41~50岁组占42.6%,51~60岁组占29.7%,多以乳腺肿块为首发症状,肿瘤直径平均3.2cm。浸润性导管癌占89.9%,淋巴结转移率52.7%。ER阳性率67.6%,PR阳性率60.8%,c-cerbB-2阳性率52.7%,c-erbB-2表达与ER、PR表达及肿瘤大小有相关性。结论本地区乳腺癌好发于41~60岁的妇女,有年轻化趋式,确诊时多数有淋巴结转移。需加强乳腺癌普查工作,早期发现,早期治疗。
作者 黄贞强
出处 《中国校医》 2013年第6期422-423,共2页 Chinese Journal of School Doctor
  • 相关文献

参考文献5

二级参考文献37

  • 1田秀娟.pS2蛋白雌激素受体孕激素受体表达与乳腺癌组织学分级预后的关系[J].山西医药杂志,2005,34(4):283-285. 被引量:1
  • 2杨玲,李连弟,陈育德,D.M.Parkin.中国乳腺癌发病死亡趋势的估计与预测[J].中华肿瘤杂志,2006,28(6):438-440. 被引量:279
  • 3Jensen MD, Esteve J, Moiler H. Cancer in the European community and its member states [J]. EurJ Cancer, 1990,26(11-12):1167- 1256. 被引量:1
  • 4Cho HS, Mason K, Ramyar KX, et al. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab[J]. Nature, 2003,421 (6924): 756 - 760. 被引量:1
  • 5Steeg PS,Bevilaequa G, Kopper L, et al. Evidence for a novel gene associated with low tumor metastasis potential[J].J Natl Cancer Inst, 1988,80(3):200 - 204. 被引量:1
  • 6Liotta LA,Steeg PS. Clues to the function of nm23 and AWD proteins in development , signal transduction and tumor metastasis provided by studies of dictyostellum discoideum[J]. J Natl Cancer Inst, 1990, 82 (14) : 1170 - 1178. 被引量:1
  • 7Wright C, Nichoison S, Angus B, et al. Relationship between e-erbB-2 protein product expression and response to endocrine therapy in advanced breast eaneer[J]. Br J Cancer, 1992,65(1):118-121. 被引量:1
  • 8Ferlay J, Shin HR, Bray F, el al. GI,OBOCAN 2008 vl. 2,cancerincidence arid morlality worldwide : IARC CancerBase No. 10. Lyon: International Agency tbr Research on Cancer, 2010. 被引量:1
  • 9Jensen OM, Parkin DM, MacLennan R, et al. Cancer registration : principles and methods. Lyon: International Agency for Research on Cancer, 1991:101-107. 被引量:1
  • 10Parkin DM, Chen VW, Ferlay J, et al. Comparability and quality control in cancer registration. Lyon: International Agency for Research on Cancer, 1994:35-49. 被引量:1

共引文献182

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部