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双介入化疗联合精准肝切除术在原发性肝癌治疗中的应用 被引量:4

Application of double interventional chemoembolization combined with precise liver resection in patients with primary liver cancer
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摘要 目的探讨经肝动脉、门静脉化疗栓塞,肝段染色联合精准肝切除术在原发性肝癌手术治疗中的安全性和有效性。方法对我院2010年3月-2011年1月收治的需手术切除的60例原发性肝癌患者随机分为2组,治疗组30例,对照组30例。治疗组开腹后先在DSA引导下,行门静脉置管、肝动脉置管、肝段染色,以确定切除范围,并在双化疗栓塞后行精准肝切除。对照组则采用常规肝切除术。比较两组手术时间、术中出血量、手术并发症及死亡率、住院时间和术后1年期复发率。结果治疗组与对照组的手术时间比较,有显著性差异(P<0.05);与对照组比较,治疗组的肝门阻断时间明显缩短,术中失血量明显减少,差异具有显著统计学意义(P<0.05);治疗组手术死亡率、住院时间、术后1年期复发率明显降低(P<0.05)。结论应用经肝动脉、门静脉化疗栓塞,肝段染色联合精准肝切除术,在原发性肝癌手术治疗中,可明显减少术中出血,缩短患者住院时间,降低手术死亡率及复发率。 Objective To investigate the safety and efficiency of the method that on application of double interven- tional chemoembolization combined with precise liver resection in patients with primary liver cancer. Methods From Mar. 2010 to Jan. 2011,60 cases those need hepatectomy were divided into two groups: the control group (n = 30) and the theropy group (n = 30). The theropy group was performed liver resection under uhrosound guided hepatic segmental staining by portal vein catherization and double interventional chemoembolization. The control group was only given hep- atectomy. The operation time, the first hepatic portal blocking time, bleeding volume, death rate and the complication were compared between the two groups. Results There was significant difference in the operartion time between two groups (P 〈 0.05). The first hepatic portal blocking time, bleeding volume, death rate and the complication in the theropy group showed more distinctive advantage than the control group with the significant difference statistically (P 〈 0.05). Conclusion Double interventional chemoembolization combined with precise liver resection can reduce the bleeding volume, the complication and death rate.
出处 《胃肠病学和肝病学杂志》 CAS 2013年第7期635-636,共2页 Chinese Journal of Gastroenterology and Hepatology
关键词 精准肝切除术 介入化疗栓塞 肝段染色 Precise liver resection Interventional chemoembolization Hepatic segmental staining
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