摘要
目的了解学龄儿童铁(Fe)、锌(Zn)膳食水平及其对感染易感性的影响。方法选取1 023名1～6年级学生进行一般情况、膳食摄入和反复呼吸道感染(RRTI)患病情况调查和评价;每年级抽取1个班共262名学生经家长知情同意后采静脉血测定免疫功能指标。结果学龄儿童Zn平均摄入量达到推荐摄入量(RNI)的60%～80%,各年龄段摄入充足的仅占20%～30%,Fe的摄入量达适宜摄入量(AI)的100%～180%,但来源于血红素铁仅占9.9%;儿童免疫指标CD3+细胞百分比、CD4+/CD8+和IgA水平均低于参考值,患反复呼吸道感染率为13%;当Zn摄入水平分别达到80%RNI、80%RNI、60%RNI、40%RNI以上时,受其影响的CD4+、CD4+/CD8+、IgA、IgM等免疫指标水平分别达到正常值范围;当Fe摄入水平分别达到200%AI、120%AI、160%AI以上时,受其影响的CD3+、IgA和IgM水平分别达到正常值范围。结论 >50%学龄儿童Zn摄入不足,Fe食物来源较差;Zn、Fe摄入水平分别至少≥80%RNI和≥200%AI时,各免疫指标才能维持在正常水平。
Objective To examine the effects of children’s nutrition condition of zinc（Zn） and iron（Fe） on status of immunization indicators.Methods A total of 1 023 students of 1-6 grades were investigated about their general state of health,5 days diet and 1 month food frequency,recurrent respiratory tract infection（RRTI） status and 262 children’s immune indicators were determined after informing the consent to their parents.Results The average intakes of Zn,Fe were 60%-80% of the recommended nutrient intake（RNI） and the rates of adequate intake（AI） were 20%-30%.The intake of Fe was adequate,but only 9.9% of the Fe was from heme-iron.The results of immunization indicator detects showed that the percentages of CD3＋ cells,the ratio of CD4＋/ CD8＋,IgA,and IgM were all below the reference value among the students.The incidence of RRTI was 12.6 %.The CD4＋,CD4＋/CD8＋,IgA and IgM were at the normal level for the students with the Zn intake level ≥80% of RNI or the Fe intake level ≥200% of AI.Conclusion The intakes of Zn and hme-iron were lower for the most of the students.The studetns immune levels are normal when their Zn intake ≥80% of RNI or their Fe intake ≥200% of AI.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2013年第7期975-978,共4页
Chinese Journal of Public Health
基金
河北省医学科学研究重点课题计划资助项目(08178)
关键词
学龄儿童
铁
锌
摄入量
免疫指标
回归分析
school children
Fe
Zn
intake
immunity indicator
regression analysis
