摘要
目的:比较分析维生素B6、654-2、碳酸氢钠在减轻阿奇霉素胃肠道反应中的效果。方法:随机选取儿科呼吸道感染的150例患儿,分为A组、B组和C组,每组各50例,在使用阿奇霉素的同时,分别加用维生素B6、654-2、碳酸氢钠以减轻患儿胃肠道反应,比较用药后,三组胃肠道不良反应整体发生情况和发生程度。结果:在恶心、呕吐、腹泻及腹痛几种不良反应症状上,A组较之B组发生率明显降低,差异有统计学意义(P<0.05),B组和C组比较差异无统计学意义(P>0.05);在不良反应发生程度上,A组较之B组发生程度明显降低,差异有统计学意义(P<0.05),B组和C组比较差异无统计学意义(P>0.05)。整体比较,A组不良反应情况发生率和发生程度均相对更低,差异有统计学意义(P<0.05)。结论:在减轻阿奇霉素胃肠道反应中,维生素B6较之654-2和碳酸氢钠整体效果相对更佳,更值得临床推广应用。
Objective：To compare the vitamin B6 ,654-2,sodium bicarbonate in the azithromycin reaction of gastrointestinal tract effect. Method：Selected 150 cases whose respiratory tracted infection randomly from pediatric.And they were divided into group A,group B and group C, each group had 50 cases.On the basic treatment using azithromycin,supplemented with vitamin B6 ,654-2,sodium bicarbonate,in order to reduce gastrointestinal reaction,then compared the overall situation of gastrointestinal adverse reaction and occurrence degree of three groups after treatment using drug.Result：In nausea,vomiting,diarrhea and abdominal pain several adverse symptoms,group A was significantly lower than the group B, with significant difference（P ＆lt;0.05）,the difference between group B and group C was not significant（P ＆gt;0.05）;the occurrence of the adverse reactions, group A was significantly lower（P ＆lt;0.05）than the B group,between group B and group C were not significant（P ＆gt;0.05）.Overall,the group A of adverse reaction incidence and degree of occurrence were relatively lower,with significant difference（P ＆lt;0.05）.Conclusion：In the azithromycin in gastrointestinal tract reaction,the overall effect of vitamin B6 with654-2 sodium bicarbonate and relatively better,more worthy of clinical application.
出处
《中国医学创新》
CAS
2013年第19期30-31,共2页
Medical Innovation of China
