摘要
目的 观察荆花胃康胶丸与雷贝拉唑、多潘立酮联合治疗反流性食管炎的疗效.方法 随机将288例反流性食管炎患者分为观察组和对照组各144例.对照组患者服用雷贝拉唑钠肠溶胶囊10mg,bid;多潘立酮片10 mg,tid,均为餐前半小时服用.观察组在对照组的基础上加用荆花胃康胶丸160mg,tid.连续治疗8周.对比两组患者临床症状评分及治疗前后内镜改善情况.结果 治疗前后临床症状变化：观察组患者治疗8周后的症状总有效率为89.6％（129/144）,对照组为60.4％（87/144）.治疗前后胃镜下食管炎愈合及炎症改善情况：观察组总有效率为91.7％（132/144）,对照组为64.6％（93/144）.结论 荆花胃康胶丸联合雷贝拉唑、多潘立酮治疗反流性食管炎疗效肯定.
Objective To observe the curative effect of Jinghua Weikang capsules combined with Rabeprazole and Domperidone combination therapy in the treatment of reflux esophagitis.Methods 288 cases of reflux esophagitis were randomly assigned into observation group （144 cases） and control group （144 cases）.The control group was treated with Rabeprazole sodium enteric-coated capsules 10 mg,twice a day; Domperidone tablets 10 mg,3 times a day.Both tablets were taken half an hour before meals.Compared to treatment measure in control group,the observation group was added with Jinghua Weikang capsules 160 mg,3 times a day,lasting for 8 weeks.Then we compared two group patients＇ clinical symptoms and improvement in endoscopic appearance after treatment.Results Clinical effective rate in observation group was 89.6 % （129/144）,clinical effective rate in control group was 60.4% （87/144）.Endoscopic esophagitis healing and inflammation improving situation：observation group 97.1% （132/144）,control group 64.6% （93/144）,both were significantly different （P〈0.05）.Conclusion Jinghua Weikang capsules combined with Rabeprazole and Domperidone has good curative effect in the treatment of reflux esophagitis.
出处
《国际医药卫生导报》
2013年第14期2116-2118,共3页
International Medicine and Health Guidance News
关键词
荆花胃康胶丸
雷贝拉唑钠肠溶胶囊
多潘立酮
反流性食管炎
Jinghua Weikang capsules
Rabeprazole sodium enteric-coated capsules
Domperidone
Reflux Esophagitis
