摘要
目的 了解老年上消化道溃疡（PU）出血的现状,探讨其可能影响因素,为临床治疗和开展有效干预提供依据.方法 采用回顾性分析方法,选取2008年1月至2012年12月在广州市番禺区何贤纪念医院确诊的PU患者共331例为研究对象,按年龄分为老年组（≥60岁）114例和非老年组（＜60岁）217例,对两组患者的发病原因和并存疾病进行比较分析.结果 老年组（占50.88％）两种以上基础疾病患病率高于非老年组（占16.13％）,差异有统计学意义（P＜0.01）.精神紧张或劳累过渡、吸烟史和饮酒史的发生率非老年组均高于老年组,差异有统计学意义（P＜0.01）.非老年组（占44.74％）幽门螺杆菌（HP）感染率高于老年组（占61.75％）,差异有统计学意义（P＜0.01）.老年组服用降压药、抗凝药、非甾体抗炎药（NSAIDs）及合用多种药物者的比例均高于非老年组,差异均有统计学意义（P＜0.01）.结论 积极治疗基础疾病,合理使用降压药、抗凝药及NSAIDs药物对防治老年PU出血有重要意义.
Objective To provide support for clinical treatment and effective prevention of ulcer hemorrhage in upper digestive tract by exploring the current status of this condition in elderly people and exploring the possible influencing factors.Methods The data on 331 patients who had been diagnosed in our hospital during the period of January 2008 to December 2012 were retrospectively analyzed.The patients were divided into elderly group （≥60 years,114 patients） and non-elderly group （〈 60 years,217 patients） according to their ages.The etiologies and coexisting diseases were analyzed and then compared between the two groups.Results The rate of two or more coexisting diseases was higher in the elderly group than in the non-elderly group （50.88% vs.16.13%,P〈0.01）.The rates of mental stress or overstrain and history of smoking and alcohol drinking were higher in the non-elderly group than in the elderly group,with a significant statistical difference （P〈0.01）.The rate of Helicobacter pylori infection was higher in the non-elderly group than in the elderly group （44.74% vs.61.75%,P〈0.01）.The percentage of taking antihypertensive drugs,anticoagulant drugs,or non-steroidal anti-inflammatory drugs （NSAIDs） alone or combination therapy was higher in the elderly group than in the non-elderly group,with a significant statistical difference （P〈0.01）.Conclusions Active treatment of underlying diseases,rational uses of antihypertensive drugs,NSAIDs,and anticoagulant agents are of important significance in the prevention and treatment of ulcer hemorrhage in upper digestive tract.
出处
《国际医药卫生导报》
2013年第13期1933-1936,共4页
International Medicine and Health Guidance News
关键词
老年
上消化道出血
现状
影响因素
Elderly
Hemorrhage in upper digestive tract
Status
Influencing factors
