摘要
以L-苯丙氨酸(L-Phe)、L-色氨酸(L-Trp)和L-亮氨酸(L-Leu)3种常见的氨基酸为手性源,经过酯化、缩合等步骤制备3种手性功能单体AAc-L-Phe(AAc:丙烯酸)、AAc-L-Trp和AAc-L-Leu,其结构经过IR、1H NMR确证。并将手性单体AAc-L-Phe与温敏材料N-异丙基丙烯酰胺(NIPAam)共聚,制备了手性共聚物P(NIPAam-co-AAc-L-Phe),结构经IR确证,示差扫描量热分析测试证明其具有温敏性。这些手性功能单体有可能用于制备环境响应性手性高分子聚合物。
Three chiral functional monomers containing L-phenylalanine （L-Phe）, L-tryptophane （L-Trp） and L-leucine（L-Leu） were designed and synthesized and used as precursors for preparing of chiral polymers. After esterification and condensations, AAc-L-Phe （AAc： acrylic acid ）, AAc-L-Trp and AAc-L-Leu were obtained and characterized by IR and 1H NMR. Then the subsequent copolymerization between AAc-L-Phe and N-isopropylacrylamide （NIPAam） was carried out in different mass ratio. The resulted polymers were identified by IR and differential scanning calorimetry（DSC） and proved that all of them are optical active and thermo-sensitive materials. The successful synthesis of chiral polymers suggested that these chiral monomers can be applied to the preparation of chiral polymers.
出处
《应用化学》
CAS
CSCD
北大核心
2013年第7期740-744,共5页
Chinese Journal of Applied Chemistry
基金
国家自然科学基金(20904039)
天津市应用基础及前沿技术研究计划(10JCYBJC02900)资助项目
关键词
手性
L-氨基酸
合成
手性单体
共聚物
chirality, L-amino acids, synthesis, functional monomers, copolymer
