摘要
以N-甲基吡唑为原料,加热下在I2/KIO3溶液中碘化,后经纯硝酸硝化得到1-甲基-3,4,5-三硝基吡唑(MTNP)。用红外光谱、核磁、元素分析对产物结构进行了表征,讨论了加料次序对碘代反应结果的影响及硝化温度对硝基取代位置的影响,得到最优加料次序并合成出硝基吡唑衍生物。对制备目标产物的硝化反应条件进行了研究,最佳反应温度为80～83℃。
1-Methyl 3,4,5-trinitropyrazole（MTNP） was synthesized using N-methylpyrazole as starting material via iodination of I2/KIO3 aqueous solution at heating temperature and nitration of 100 % HNO3. Its structure was char acterized by IR, MS and elemental analysis. The effects of feeding sequence on the iodo reaction results and nitration temperature on nitro-substituent position were investigated. The optimum feeding sequence was obtained and the ni tropyrazole derivatives were synthesized. The nitration reaction conditions for the target product were studied. The optimal reaction temperature was considered as 80 83℃.
出处
《火炸药学报》
EI
CAS
CSCD
北大核心
2013年第3期28-30,共3页
Chinese Journal of Explosives & Propellants
