摘要
目的探讨体液标本的病理检查方法及免疫组化在其诊断中的应用。方法回顾性观察148例体液离心沉淀细胞块的常规HE染色结合免疫组化染色,分析体液离心沉淀细胞块的病理特点。结果 148例体液离心沉淀物标本中,镜下形态结合免疫组化染色结果诊断为恶性的病例有65例,能明确组织来源的病例60例,其中肺癌45例,卵巢癌6例,胃肠道癌3例,其余11例;体液离心沉淀细胞块诊断与手术切除标本诊断符合率为95.5%。结论结合临床病史及HE形态选择恰当的免疫标记有助于肿瘤的诊断,确定组织来源,对无手术指征的肿瘤患者具有重要的价值。
Objective To investigate the methods of pathological examination on body fluids cell blocks and effects of immunohistoehemistry in its diagnosis. Methods The HE and immunohistochemical staining of the body fluids cell blocks were used to analyse the clinical pathological features of 148 cases. Results There were 65 cases malignant lesions in 148 body fluids cell blocks according to microscopic morphology and immunohistochemical staining. In the malignant cases, there were 60 cases had defined tissue sources, including 45 cases of lung cancer, six ovarian cancer,3 gastrointestinal cancer and 11 other cases. The coincidence rate between the body fluids cell blocks diagnosis and surgical specimen diagnosis was 95.50/00. Conclusion To selecte some appropriate immune markers according to clinical history and HE morphology can help the tumor diagnosis and to determine the tissue origin. The examination of body fluids cell blocks is important for turnout patients without indications for surgery.
出处
《成都医学院学报》
CAS
2013年第3期316-317,共2页
Journal of Chengdu Medical College
关键词
体液
细胞块
免疫组织化学
Body fluids
Cell blocks
Immunohistochemistry