摘要
目的探讨影响南昌地区儿童手足口病发生及进展为重型的危险因素,为防控儿童手足口病提供依据。方法选取南昌地区某大型儿童医院(江西省儿童医院)2012年1月1日至6月30日发病的重型手足口病患儿275例,普通型手足口病患儿200例及同期非肠道病毒感染儿童210例,经知情同意后调查研究对象个人生活习惯及就诊信息,对手足口病相关因素进行单因素及多因素条件Logistic回归分析。结果年龄、病前10d到过医疗单位、居住在农村与手足口病的发生有关;年龄、居住在城镇、EV71感染是手足口病发展为重型的影响因素。结论为降低手足口病的发病率和病死率,应加强手足口病的预防和控制,并注意与患儿的隔离。
Objective To explore the influence factors for common or severe hand-foot-mouth disease（HFMD）in Nanchang district in an attempt to provide scientific evidence for prevention and control of this disease.Methods A total of 275 severe HFMD cases,200 common HFMD cases and 210 non-HFMD controls were selected from a comprehensive children’s hospital in Nanchang district in 2012.All the subjects were interviewed with the unified questionnaires.Single and multivariate conditional Logistic regression was carried out to evaluate the effects of the related factors on the basis of odds ratio（OR）and 95% confidence interval（95% CI）.Results It was found that age,medical visit 10 days before onset,rural dwelling were related to the occurrence of HFMD.Age,urban dwelling and EV71 infection were related to the progression of HFMD to a severe case.Conclusion Prevention and control of HFMD should be enhanced to reduce the morbidity and mortality of this disease and meanwhile,the diseased children should be isolated.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2013年第3期359-364,共6页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
