摘要
目的比较不同影像引导频度对不同部位肿瘤放疗精度的影响。方法将头部、头颈部、胸部、腹盆部各20例患者接受螺旋断层放疗的前20次放疗前采集的1600套影像引导图像与计划图像进行配准。所有患者均分别进行隔天方案、每5天方案与每天方案的摆位误差数据统计,分析隔天方案和每5天方案与每天方案的摆位误差修正值的偏差及4个部位的不同的影像引导频度方案的三维摆位误差超过3mm和5mm的频度。结果每5天方案在左右、头脚和上下方向摆位误差的差值分别为:(0.42±0.06)mm、(0.68±0.09)mm、(0.28±0.04)mm(头部),(0.40±0.06)mm、(0.29±0.12)mm、(0.23±0.13)mm(头颈部),(0.87±0.12)mm、(1.85±0.16)mm和(0.79±0.11)mm(胸部),(0.83±0.12)mm、(0.19±0.31)mm和(0.95±0.16)mm(腹盆部)。隔天方案中头部、头颈部、胸部和腹盆部的三维摆位误差超过3mm的频度分别为12.25%、18%、23%和25%,超过5mm的频度分别为3.25%、4.25%、12%和13.75%;每5天方案中头部、头颈部、胸部和腹盆部的三维摆位误差超过3mm的频度分别为21.75%、24.5%、36%和34%,超过5mm的频度分别为5%、8.25%、23%和24.75%。每5天方案的摆位误差大于隔天方案(P<0.05)。结论提高影像引导频度可提高各个部位的肿瘤放疗精度。
Objective To evaluate the precision of different image guide frequency protocol in the treatment of tumors at dif- ferent positions. Methods Sixteen thousands sets of megavoltage CT（MVCT） images were collected from 80 patients with tumors at different positions before 20 treatment fractions, including 20 brain, 20 head and neck（H＆N） , 20 thoracic and 20 abdomino-pelvis. The MVCT images of different guide protocols and planning images were matched as to analyze either the deviation value of every five days protocol and daily protocol or the deviation value of every other day protocol and daily protocol. Meanwhile, the frequency of three-dimensional positioning error more than 3mm and 5mm in four different positions were investigated. Results The deviations be- tween every five days protocol and every other day protocol on lateral, longitudinal, vertical were （ 0. 42±0.06 ） mm, （ 0. 68 ± 0. 09 ） mm, （ 0. 28±0. 04 ） mm for the brain tumors ; （0. 40 ±0. 06 ） mm, （0. 29± 0. 12 ） mm, （0. 23 ±0. 13 ） mm for H＆N ; （ 0. 87±0. 12 ） mm, （ 1.85±0. 16 ） mm, （ 0.79±0. 11 ） mm for thoracic ; （ 0. 83±0. 12 ） mm, （ 0. 19± 0. 31 ） mm, （ 0. 95± 0. 16 ） mm for abdomino-pelvis. In the every other day protocol： for brain treatments, 12. 25% and 3.25% of treatment fractions were shifted 3mm and 5mm 3 dimen- sion（3D） vector distance; For H＆N treatments, 18% and 4. 25% of treatment fractions were shifted 3mm and 5ram 3D vector dis- tance; For thoracic treatments, 23% and 12% of treatment fractions were shifted 3mm and 5mm 3D vector distance; For abdomino- pelvis treatments, 25% and 13.75% of treatment fractions were shifted 3mm and 5mm 3D vector distance. Whereas this occurred for 21.75% and 5% ,24. 5% and 8. 25%, 36% and 23%, 34% and 24. 75% of brain, H＆N, thoracic and abdomino-pelvis. The devia- tion values of every five days protocol were higher than those of every other day protocol（ P 〈 0. 05 ）. Conclusion Improving the image guide frequency can
出处
《临床肿瘤学杂志》
CAS
2013年第6期544-548,共5页
Chinese Clinical Oncology
