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奥曲肽联合凝血酶在肝硬化合并上消化道出血患者中的应用 被引量:19

The Clinical Application of Octreotide Combined Thrombin on Patients with Cirrhosis Complicated with Upper Digestive Tract Hemorrhage
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摘要 目的探讨奥曲肽联合凝血酶在肝硬化合并上消化道出血患者中的应用效果。方法选择该院50例肝硬化合并上消化道出血患者,随机分为观察组和对照组。观察组给予奥曲肽、奥美拉唑和凝血酶治疗,对照组给予奥曲肽和奥美拉唑。观察两组患者止血时间和便血持续时间。结果观察组止血时间和便血持续时间分别低于对照组,差异有统计学意义(P<0.05)。观察组总有效率为96.0%,对照组总有效率为76.0%,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论奥曲肽联合凝血酶在肝硬化合并上消化道出血中的止血效果显著,值得借鉴。 Objective To explore the clinical affect of octreotide combined thrombin on patients with cirrhosis complicated with upper digestive tract hemorrhage. Methods Fifty case with cirrhosis complicated with upper digestive tract hemorrhage were selected and randomly divided into observation group and control group. The observation group was treated with octreotide, omeprazole and thrombin, octreotide and omeprazole was given to control group .bleeding time and hematochezia duration. were observed in two groups. Results The hemostatic time and bleeding time in the observation group were lower thanthose in the control group, the difference was statistically significant (P&lt;0.05). The total effective rate in the observation group was 96%, The total effective rate in the control group was76%,the total effective rate of observation group is higher than that of the control group, the difference was statistically significant(P&lt;0.05). Conclusion Octreotide combined with thrombin on cirrhosis complicated with upper digestive tract hemorrhage has significant hemostatic effect.
作者 曾德映
出处 《中外医疗》 2013年第16期33-34,共2页 China & Foreign Medical Treatment
关键词 肝硬化 上消化道出血 奥曲肽 凝血酶 Liver cirrhosis Upper gastrointestinal bleeding Octreotide Thrombin
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