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B型脑钠肽在高危人群中早期诊断孤立性左心室舒张功能障碍的价值 被引量:1

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摘要 目的评估血浆BNP水平在高危人群中早期诊断孤立性左室舒张功能障碍的价值。方法纳入72例高血压、糖尿病、高血脂以及缺血性心脏病患者。脉冲多普勒(PW)获取二尖瓣口血流速率E/A、E峰下降时间(DT)与等容舒张时间(IVRT)。并检测所有患者的血浆BNP水平。根据E/A、DT、IVRT值分为两组:左心室舒张功能正常组和孤立性舒张功能障碍组。结果左心室舒张功能正常组的血浆BNP值为(42.1±7.6)pg/ml,而舒张功能不全组为(185.5±26.5)pg/ml,两组间有明显差异(P<0.01)。BNP检测孤立性左心室舒张功能障碍ROC曲线下面积0.93(95%CI,0.86 to 0.99;P<0.01)。BNP值为63pg/ml,其特异性为90.5%,敏感性91.3%,准确率为90.3%。结论血浆BNP水平检测有助于早期诊断孤立性左心室舒张功能障碍。
出处 《心脑血管病防治》 2013年第3期219-221,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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