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以高钙血症首发的B细胞淋巴瘤白血病2例报告并文献复习

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摘要 目的探讨非霍奇金淋巴瘤(NHL)并发高钙血症患者的临床特点。方法报告我科收治的2例以高钙血症为首发表现的NHL的诊治经过,并进行相关文献复习。结果 2例患者均为B细胞型,属侵袭性,累及骨髓达白血病期,血钙浓度最高分别为4.93mmol/L、3.6mmol/L,甲状旁腺激素降低,血β2微球蛋白、LDH均明显升高,不伴随骨损害。1例在化疗1个疗程后复查骨髓已缓解但出现中枢侵犯,病情进展;1例在化疗次日渐出现呼吸困难、成人呼吸窘迫综合征。2例患者最终均因并发严重的感染死亡。结论 NHL并发高钙血症常见于中高度NHL,常伴有血清β2微球蛋白、LDH升高,肿瘤细胞高负荷,预后不良。
出处 《福建医药杂志》 CAS 2013年第3期46-48,共3页 Fujian Medical Journal
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参考文献10

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