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细胞内铜转运系统的研究进展(综述) 被引量:3

Advances in Intracellular Copper Transport System
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摘要 铜是人体必需的营养元素,参与体内许多重要的生化反应。细胞内多种铜转运蛋白和伴侣蛋白参与了铜离子的吸收、转运和清除,形成了一个复杂的铜转运系统。铜转运系统中的铜转运蛋白和/或伴侣蛋白功能异常与多种疾病的发生、发展关系密切。近年来,铜代谢障碍相关疾病越来越受到人们的重视,对铜转运系统相关蛋白的研究也不断深入。 Copper is an essential nutrient elements and it participates in many important biochemical reactions in the body. A variety of copper transport proteins and copper chaperone proteins take part in the absorption, transport and removal of copper ions, which forms a complex copper transport system. Many diseases were found to be closely related to dysfunction of copper transporter proteins or copper chaperone proteins in the copper transport system. In recent years, more attention is paid to the diseases associated with abnormal copper metabolism and more research is focused on the proteins which is related to copper transport system.
出处 《安徽卫生职业技术学院学报》 2013年第3期78-79,81,共3页 Journal of Anhui Health Vocational & Technical College
基金 国家自然科学基金项目(项目编号:81072738)
关键词 铜转运系统 铜伴侣蛋白 WILSON病 MENKES病 Copper transport system Copper chaperone Wilson's disease Menkes' disease
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