摘要
目的观察泪道插管联合丝裂霉素C和妥布霉素地塞米松眼膏治疗泪道阻塞疗效。方法将78只眼泪道阻塞患者随机分为两组：A组40只眼，行丝裂霉素＋妥布霉素地塞米松眼膏＋泪道插管；B组38只眼（对照组），行单纯性泪道插管，观察两组疗效，A组首先向泪道注入浓度为0．2mg／ml的丝裂霉素C0．2ml，5min后彻底冲洗，随后向泪道注满妥布霉素地塞米松眼膏，B组行单纯性泪道插管。结果随访6-9个月，术后1、3个月的A组治愈率均为100％，B组分别为89．5％、81．5％，6、9个月的A组治愈率均为95％，B组分别为73．7％、71．1％，两组差异有统计学意义（P〈0．05），A组显著高于B组。结论泪道插管术中联合丝裂霉素C和妥布霉素地塞米松眼膏可明显提高术后长期治愈率。
Objective To observe the lacrimal intubation with mitomycin and TobraDex Ophthal- mic ointment （TDO） in the treatment of lacrimal passage obstruction. Methods Senventy-eight eyes with obstruction of lacrimal passage were randomly divided into group A （40 eyes, MMC＋TDO） and group B （38 eyes, control group）. In group A, 40 eyes firstly applied 0.2mg/ml MMC, washed thoroughly after 5 minutes, then filled up TobraDex Ophthalmic ointment. In group B, 38 eyes only conducted Lacrimal duct intubation. Results All patients were followed up for 6-9 months. After 1 month and 3 months treatment, the healing rates of group A were 100%, group B 89.5%, 81.5% respectively; after 3 and 9 months, the healing rates of group A were 95%, group B was 73.7%, 71.1% respectively, there was a great significantly difference between the two groups （P 〈0.05）, group A was significantly higher than that of B group. Conclusions Mitomycin C combined with TobraDex Ophthalmic ointment can significantly improve the healing rate on patients of LDCL in long term.
出处
《中国实用眼科杂志》
CSCD
北大核心
2013年第6期763-765,共3页
Chinese Journal of Practical Ophthalmology
关键词
泪道阻塞
插管
丝裂霉素C
妥布霉素地塞米松眼膏
Lacrimal passage obstruction
Duct intubation
Mitomycin C
TobraDex Ophthalmicointment
