摘要
目的分析支气管色素沉着纤维化的临床特点及发病原因。方法对4例支气管色素沉着纤维化患者的病史、影像学特征、气管镜下表现及病理特征等进行分析，并结合文献加以总结。结果气管镜下表现为支气管黏膜有不同程度的黑色素沉着，多叶、段支气管有较明显的支气管狭窄或闭塞。肺CT多表现为肺内斑片实变影、纵隔或肺门淋巴结肿大、肺内弥漫性小结节影、支气管狭窄及肺不张，易误诊为肺癌。病理表现为支气管黏膜慢性炎症或肉芽肿伴黑色素沉着，支气管周围严重纤维化。结论支气管色素沉着纤维化是一种临床综合征，结核、尘肺、自身免疫性疾病等均可能出现此种表现。
Objective To explore the cause and clinical manifestation of bronchial anthracofibrosis. Methods The clinical features, radiological findings, bronchoscopic natures, and histological characteristics of four cases of bronchial anthracofibrosis were analyzed and summarized, and the relevant literatures were reviewed. Results The principal finding of bronchoscopy was anthracotic pigmentation of bronchial mucosa with bronchial stenosis. Chest CT revealed lobal or segmental consolidation, segmental or subsegmental atelectasis, calcified and uncalcified lymph nodes. Pathologic examination of the specimens obtained by bronchoscopic biopsy showed chronic mucosal inflammation, or granulomatous inflammation, dense mucosal fibrosis with anthracotic pigmentation. Conclusions Bronchial anthracofibrosis is a clinical syndrome rather than a disease. The precise cause of bronchial anthracofibrosis is unknown. Bronchial anthracofibrosis might be associated with active or old tuberculosis, mineral dust exposure and autoimmune diseases.
出处
《国际呼吸杂志》
2013年第12期901-905,共5页
International Journal of Respiration
