摘要
目的 配对测定脐血、胎发、胎盘、母发汞含量，分析其相关性以及各种汞暴露高危因素对样本汞含量的影响。方法 对整个孕期生活在本地、无重大疾病史的入院孕妇进行健康影响因素问卷调查，所分娩新生儿（除多胎、出生缺陷外）娩出时收集脐血、胎发，同时采集胎盘组织及产妇头发行汞含量测定。结果 303例脐血、胎发、胎盘、母发汞含量均值分别为1.65 μg/kg、234.58 μg/kg、3.85 μg/kg、497.62 μg/kg，50百分位数分别为1.72 μg/kg、252.24 μg/kg、3.98 μg/kg、508.88 μg/kg。脐血汞和胎发汞、脐血汞和胎盘汞、脐血汞和母发汞、胎发汞和胎盘汞、胎发汞和母发汞、母发汞和胎盘汞均呈正相关（P均〈0.05）。生活在涉汞工厂附近、较多食用淡水鱼或海鱼、孕期使用增白类化妆品、接触生活燃煤和香烟等高危因素者脐血汞、胎发汞、母发汞分别为（2.24±0.20）μg/kg、（315.65±35.31）μg/kg、（663.53±71.83）μg/kg，未接触者分别为（1.62±0.16）μg/kg、（245.79±28.21）μg/kg、（499.39±47.72）μg/kg，2组间差异均有统计学意义（P均 〈0.01）。结论 除地区性加强工业污染监控和治理外，孕期应增强保健意识，生活中避免接触汞暴露高危因素。脐血汞和胎发汞不仅高度相关，且均与产妇胎盘汞、母发汞显著相关。2种检测均能达到监测宫内汞暴露状况的目的。
Objective To determine mercury contents in pair in cord blood, fetal hair, placenta and maternal scalp hair, and to analyze the correlation among them and the effect of mercury exposure risk factors in the mercury con-tents of samples. Methods Puerperants in the hospital, who lived in the local area without history of major diseases during the whole pregnancy, were investigated by questionnaire composed to several health factors. Cord blood, fetal hair, placenta and maternal scalp hair of these puerperal and their neonates （polyembryony and birth defects excluded） were collected to determine mercury content in pairs. Results The mean mercury contents of cord blood, fetal hair, pla-centa and maternal scalp hair in 303 samples were 1.65 μg/kg,234.58 μg/kg, 3. 85 μg/kg,497.62μg/kg,respec- tively. Fifty percentile of them were 1.72 μg/kg,252.24 μg/kg,3.98 μg/kg, 508.88 μg/kg, respectively. There were direct correlations between mercury in cord blood and that in fetal hair, mercury in cord blood and that in placenta, mer-cury in cord blood and that in maternal scalp hair, mercury in fetal hair and that in placenta, mercury in fetal hair and that in maternal scalp hair, mercury in maternal scalp hair and that in placenta（ all P 〈 0.05 ）. The mercury contents in cord blood,fetal hair and maternal scalp hair of those living nearby factories involved in mercury, higher intake fish during the pregnancy ,firing coal and consumption of whiting cosmetics and smoking were determined as （2.24 ± 0.20） μg/kg, （315.65 ± 35.31 ） μg/kg and （663.53 ± 71.83） μg/kg. The mercury in those without the high risk factors mentioned above were（ 1.62 ± 0.16） μg/kg, （245.79 ± 28.21 ） μg/kg and （499.39 ± 47.72 ） μg/kg. There was a significant difference between 2 groups （ all P 〈 0.01 ）. Conclusions In addition to control industrial pollution, preg-nant women should avoid the above-mentioned high risk factors and pay more attention to health care during pregnancy. The mercury content in
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2013年第11期820-822,共3页
Chinese Journal of Applied Clinical Pediatrics
关键词
脐血
胎发
母发
胎盘
汞
妊娠
危险因素
Cord blood
Foetal hair
Maternal scalp hair
Placenta
Mercury
Pregnancy
High risk factor
