摘要
目的 对重度阻塞性肺气肿患者肺减容手术 (LVRS)后呼吸困难指数、运动能力、生活质量进行评价。方法 采用体容积描记仪、运动心肺功能仪对 10例患者术前及术后 3、6、12个月肺功能、运动心肺功能及 6分钟步行距离 (6MWD)进行测定。并用简易医学研究委员会呼吸困难评分标准及诺丁汉姆健康状况标准 (NHP)对呼吸困难程度及生活质量进行评价。结果 术后 3、6、12个月与术前相比 ,用力肺活量 (FVC)、一秒钟用力呼气容积 (FEV1)及最大通气量 (MVV)均增加 ,P <0 0 1;残气容积 (RV)、肺总量 (TLC)及残总比 (RV/TLC)均降低 ,P <0 0 1;增加负荷量 (WATT) ,总运动时间(TET) ,最大摄氧量 ( VO2 max) ,最大氧脉搏 ( VO2 max/HR) ,每分最大通气量 ( VEmax) ,最大潮气量( VTmax) ,6MWD均增加 ,P <0 0 1,肺泡弥散量 (Dco) /肺泡通气量 ( VA)无显著变化 ,P >0 0 5 ;呼吸困难分级下降 ,P <0 0 1;NHP问卷Ⅰ及问卷Ⅱ评分均降低P <0 0 5 ,<0 0 1。结论 对重度阻塞性肺气肿患者行LVRS ,可明显提高运动能力及生活质量。
Objective To evaluate grade of dyspnea, exercise performance and quality of life pre and post lung volume reduction surgery in patients with severe emphysema Methods Serial measurement of lung function, cardiopulmonary exercise test and 6 minute walk distance, and the dyspnea grade assessment by modified dyspnea scale of English Medical Research Councial and quality of life by Notting ham Health Profile were all done before and at 3, 6,12 months after surgery Results FVC, FEV 1, MVV increased ( P <0 01) and RV, TLC, RV/TLC decreased at 3,6,12 months after surgery ( P <0 01), WATT, TET, O 2max, O 2max/HR, Emax, Tmax, 6MWD were all improved ( P <0 01), and the dyspnea grade was declined as well as the NHP score( P <0 01 or <0 05) Conclusion Lung volume reduction surgery in patients with severe emphysema may improve patient′s exercise performance and quality of life
出处
《中华结核和呼吸杂志》
CSCD
北大核心
2000年第8期462-464,共3页
Chinese Journal of Tuberculosis and Respiratory Diseases
关键词
重度阻塞性肺气肿
肺减容术
运动能力
生活质量
Emphysema
Lung volumn reduction surgery
Cardiopulmonary exercise test
Quality of life
