摘要
心肌缺血后再灌可导致严重的心律失常 本文比较了山莨菪碱和U - 63557A(血栓素A2 合成酶抑制剂 )对再灌注后心律失常的作用 结果显示山莨菪碱可显著缩短室性心动过速(VT)和室颤 (VF)的持续时间 ,降低心律失常的发生率和动物死亡率 ;U - 63557A仅使VT和VF的持续时间明显缩短 本文提示山莨菪碱和U -
Reperfusions of ischemic myocardium may lead to severe arrhythmias In this study,we compared effects of anisodamine and U-63557A on reperfusion～Induced arrhythmias.The results showed that anisodamine markedly reduced the mean duration of ventricular tachycardia and fibrillation and reduced the incidences of ventricular tachycardia and fibrillation and mortality during reperfusion.U-63557A,an inhibitor of thromboxane A 2 synthetase,reduced only the mean duration of ventricular tachycardia and fibrillation.These results suggest that anisodamine and U-63557A may play some cell protective roles against reperfusion～induced arrhythmias in different degree
出处
《湖北三峡学院学报》
2000年第5期79-81,共3页
Journal of China Three Gorges University(Humanities & Social Sciences)
关键词
心律失常
山莨菪碱
心肌再灌注
Anisodamine
Reperfution
Arrhythmias
Thromboxane A 2
