摘要
目的:探索感冒后咳嗽的中医证候辨证规律。方法:通过文献查询、议题小组讨论、专家delphi法审定等步骤构建量表条目,形成初步量表。对初步的量表进行预调查,通过统计学方法对条目再次筛选,形成最终量表,并从信度和效度两方面对量表进行考评。应用最终量表多中心前瞻性收集316例感冒后咳嗽患者,采用因子分析对其四诊信息进行中医证候非线性降维研究。结果:最终形成4个维度、43个条目的量表。信度分析中,该量表总克朗巴赫α系数达0.815,半分信度分别为0.726和0.809,相关系数为0.782。效度分析中,因子分析提取4个公因子,累及方差贡献率为65.384%,而确定的4个公因子代表的维度与临床实际相符合。在提取的4个公因子中,F1为痰阻清窍,F2为肺脾两虚,F3为心阴亏虚,F4为风燥犯肺,并且初步建立了各个证候的诊断条件。结论:该量表具有较好的信度、效度,可以作为感冒后咳嗽的中医证候辨证量表。采用因子分析法对感冒后咳嗽进行中医证候的分类研究和初步建立证候诊断标准是可行的,可为本病的辨证论治提供依据。
Objective：To explore the TCM syndrome points rule of post infectious cough. Methods：The instrument was devel- oped by establishing item pool through literature consulting, item raised group discussion, Delphi expert consultation, and the reliability and validity of the scale were evaluated. 316 patients were investigated by the scale. Multicenter prospective research on TCM syndromes was done with the nonlinear dimension reduction by factor analysis. Results：A scale was developed and evaluated. The module, including 43 items, was consisted of 4 domains. In the reliability, the Cronbach ＇s alpha coefficient was 0. 815, split - half reliability was 0. 726 and 0. 809 respectively, the coefficient of split - half reliability was 0. 782. Construct validity tested by factors analysis resulted in 4 factors, which contributed to 65. 384% of total variance and 4 factors conformed to clinical observation. There were four extracted factors in factor analysis ： F1, F2, F3 and F4. F1 was phlegm obstructing nose, F2 was deficiency of both lung and spleen, F3 was yin deficiency of heart, F4 was attacking on the lung by wind and dry. The diagnostic criteria for TCM syndromes were preliminarily and respectively established. Conclusion：The scale has a good internal reliability and validity, which can be applied for the differentiation of post infectious cough. It is feasible that factor analysis was applied for syndrome elements of post infectious cough and establishing the preliminary diagnostic criteria. It was considered that the result can provide objective evidence for syndrome differentiation and treatment.
出处
《辽宁中医杂志》
CAS
2013年第6期1103-1105,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
上海市卫生局青年科研基金(2008Y126)
上海高校选拔培养
