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不同速率去氧肾上腺素预防腰硬联合麻醉下行剖宫产术产妇低血压的效果观察 被引量:15

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摘要 目的探讨不同速率去氧肾上腺素(PE)预防腰硬联合麻醉下行剖宫产术产妇低血压的临床效果。方法将80例择期行剖宫产手术的产妇随机分为对照组及PEⅠ、Ⅱ、Ⅲ组各20例,腰硬联合麻醉成功后,对照组静滴生理盐水;PEⅠ、Ⅱ、Ⅲ组将PE 5 mg加生理盐水稀释至50 mL,其静滴速率分别为25、50、75μg/min。观察各组切皮至胎儿娩出时间、术中液体输入总量、出血量、娩出前(BD)血压下降及上升例数、娩出后(AD)血压下降及上升例数及心动过缓、恶心、呕吐例数,胎儿娩出即刻的新生儿脐动脉血血气分析值及生后Apgar评分,以及PEⅠ、Ⅱ、Ⅲ组单次追加PE例数、追加PE的总量、静滴PE总量、中止静滴PE例数、PE总用量。结果与对照组比较,PE各组胎儿BD、AD的低血压发生率明显降低,高血压发生率PEⅢ组高于其他3组(P均<0.05);恶心、呕吐发生率PE各组明显低于对照组(P均<0.05);与PEⅠ、Ⅱ组比较,Ⅲ组的PE总用量、术中输注PE最多,术中需要中止的例数较多(P均<0.05);单次追加PE最多的是对照组,其次为Ⅰ组。其余观察指标各组比较P均>0.05。结论 PE可减少剖宫产产妇在胎儿BD的低血压发生率,PE 50μg/min的速率可为产妇提供更稳定的血流动力学环境。
出处 《山东医药》 CAS 2013年第17期68-70,共3页 Shandong Medical Journal
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