摘要
目的:探讨丹香冠心注射液联合杏灵分散片治疗心脉瘀阻型冠心病的临床疗效。方法:选取本院2009年6月至2012年6月收治的128例冠心病患者,将其随机分为对照组和观察组各64例。对照组采取丹香冠心注射液治疗,观察组在此基础上联合杏灵分散片治疗。两组疗程均为6周,观察并比较两组患者的临床疗效。结果:观察组的临床疗效明显优于对照组(P<0.05,P<0.01);治疗后观察组血脂水平和血液流变学指标明显优于对照组(P<0.01);观察组的硝酸甘油停用率明显高于对照组(P<0.05);两组患者不良反应比较无显著性差异。结论:丹香冠心注射液联合杏灵分散片能有效改善心脉瘀阻型冠心病心绞痛患者的血脂及血液流变性,其临床效果显著,且不良反应少,值得在临床推广。
Objective： To investigate the clinical efficacy of the Danxiang Guanxin injection combined with Xingling dispersible tablet for treating angina pectoris with heart stagnation.Method： One hundred and twenty-eight patients with angina pectoris were admitted in hospital from June 2009 to June 2012,they were randomly divided into control group and observation group（n = 64 each）.The control group was given Danxiang Guanxin injection for treatment while the observation group was received Xingling dispersible tablet on the basis of the control group.After 6 weeks,the clinical efficacy was compared between the two groups.Result： The clinical efficacy of the observation group was significantly better than that of the control group（P ＆lt; 0.05,P ＆lt; 0.01）;after the treatment,the serum lipids levels and hemorheological parameters of the observation group were significantly better than those of the control group（P ＆lt; 0.01）.Nitroglycerin discontinuation rate in the observation group was higher than that in the control group（P ＆lt; 0.05）;and the adverse reactions between the two groups showed no significant difference.Conclusion： Danxiang Guanxin injection combined with Xingling dispersible tablet can effectively improve the hemorheological parameters and serum lipids levels for the patients suffered from angina pectoris with heart stagnation.The clinical effect is significant,and has less adverse reactions,which is worth to be applied in clinic.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第12期281-284,共4页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
丹香冠心注射液
杏灵分散片
冠心病心绞痛
心脉瘀阻型
Danxiang Guanxin injection
Xingling dispersible tablet
angina pectoris
heart stagnation
