摘要
目的通过对进展性与非进展性缺血性脑卒中患者高血压病史及入院后平均动脉压的分层对比研究,为进展性缺血性脑卒中的预测提供依据。方法将入组的急性脑梗死患者按入院后病情变化分为进展组和非进展组,再按高血压病史及入院后平均动脉压情况分为若干亚组,并对结果进行统计学分析。结果高血压史20年及以上组、高血压史20年?以下组及无高血压史组任意两两比较,差异显著,且进展性卒中(SIP)发病率,前者(49.4%)>中间者(30.0%)>后者(16.8%)。平均动脉压≤75mmHg组与75mmHg<平均动脉压<165mmHg组比较,P=0.005<0.01,差异显著,且SIP发病率,前者(52.0%)明显高于后者(25.9%);平均动脉压≥165mmHg组与75mmHg<平均动脉压<165mmHg组比较,P=0.011<0.017,差异有统计学意义,且SIP发病率,前者(48.3%)明显高于后者(25.9%);平均动脉压≤75mmHg组与平均动脉压≥165mmHg组比较,P=0.785>0.017,差异无统计学意义。结论高血压病史的有无及长短均与SIP相关;平均动脉压超过一定范围,无论升高还是降低,都是SIP的危险因素。
Objective To provide a scientific basis to with prediction of progressive ischemic stroke through straticulate contrastive study on hypertension history and mean arterial pressure（MAP）of patients with progressive,non-progressive ischemic stroke.Methods The admitted patients with acute cerebral infarction were devided into two groups：SIP（stroke in progression）group and non-SIP group by changes of disease conditions after the onset,and then they were divided into several sub-groups by hypertension history and mean MAP,and the results were statistically analyzed（χ 2 test）.Results There is a significant difference between random two of group with hypertension history of 20 and more than 20 years,group with hypertension history of less than 20 and group without hypertension history,and for SIP incidence rate,the former（49.4%）the intermediary（30.0%）the latter（16.8%）.There is a significant difference between group with mean arterial pressure（MAP）≤ 75mmHg and 75mmHgMAP165mmHg,P=0.0050.01,and for SIP incidence rate,the former（52.0%）is significantly higher than the latter（25.9%）;There is a statistical difference between group with MAP ≥ 165mmHg and 75mmHgMAP165mmHg,P=0.0110.017,and for SIP incidence rate,the former（48.3%）is significantly higher than the latter（25.9%）;There is no statistical difference between groups with MAP≤ 75mmHg and MAP≥ 165mmHg,P=0.7850.017.Conclusion The history of hypertension is correlated with SIP,as well as length of history of hypertension.MAP over a certain range,regardless of higher or lower,are probably risk factors for SIP.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2013年第5期443-445,共3页
Journal of Apoplexy and Nervous Diseases
关键词
进展性脑卒中
高血压史
平均动脉压
预测
Progressive ischemic stroke
Hypertension history
Mean arterial pressure
Prediction
