低氧诱导因子与肾细胞癌相关研究进展
摘要
低氧诱导因子在肾细胞癌中高表达，但在正常氧供下会通过泛素蛋白激酶途径降解，实体肿瘤乏氧区域导致细胞的增殖、血管生成、肿瘤转移及化疗抵抗，低氧诱导因子表达的重要性可能会提高临床治疗效果及预后，本文主要对低氧诱导因子在治疗肾细胞癌的所起的作用的最新研究作一综述。
出处
《国际泌尿系统杂志》
2013年第3期367-371,共5页
International Journal of Urology and Nephrology
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