摘要
目的回顾性分析国内关于喉癌肉瘤的文献报道,总结其发病规律、临床特点及诊治经验。方法以中国知网、万方数据库、重庆维普及Pubmed为数据源,主题词为"喉癌肉瘤"、"梭形细胞癌,喉"、"喉肉瘤样癌"、"laryngeal carcino sarcoma","spindle-cell carcinoma,laryngeal","sarcomatoid carcinoma",检索国内关于喉癌肉瘤的报道。对所有病例的资料进行分析。结果共检索到喉癌肉瘤29例,男26例,女3例;年龄43～83岁。主诉以声嘶为主,29例患者均进行了组织光镜下观察,23例同时行免疫组织化学检查。17例报道了治疗情况,除1例仅行放疗外,其余均进行了手术。结论喉癌肉瘤较为罕见,诊断主要依据免疫组织化学检查,以波形蛋白和细胞角蛋白同时阳性为主要指标,治疗以手术为主,预后与多种因素有关。
OBJECTIVE To analyze the prevalence, clinical characteristics, diagnosis and treatment of domestic laryngeat carcinosarcoma by reviewing the related literatures. METHODS The terms of ＂laryngeal carcinosarcoma＂ ＂spindle-cell carcinoma, laryngeal＂ and ＂sarcomatoid carcinoma＂ were used to search all of the papers on the China national knowledge internet （CNKI） , Wanfang database, CQVIP database and Pubmed database covering all years. All of the papers were analyzed. RESULTS Twenty-two papers（29 cases） were fitted in with the keywords. All 29 patients included male 26 cases and female 3 cases, aged from 43 to 82 years. The main complain was hoarseness. Light microscopic test was performed in all cases and immunohistochemistry was done in 23 patients. The treatment history was reported in 17 cases, which were treated with surgery accepted for 1 case with simple radiotherapy. CONCLUSION Laryngeai carcinosarcoma is rare and its diagnosis is mainly based on the immunohistochemistry examination which showed simultaneously positive of vimmentin and cell keratin. Laryngectomy should be performed in patients with earlytage tumors and its prognosis is reated to various factors.
出处
《中国耳鼻咽喉头颈外科》
CSCD
2013年第5期228-230,共3页
Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词
喉
肉瘤
喉肿瘤
期刊论文(文献类型)
临床特点
Larynx
Sarcoma
Laryngeal Neoplasms
Journal Article [Publication Type]
Clinical Characteristics
