摘要
目的了解广西壮族自治区(广西)艾滋病病毒(HIV)感染者和艾滋病(AIDS)病人(HIV/AIDS病人)中,与AIDS相关死亡病例和非AIDS相关死亡病例的分布情况,以及接受AIDS抗病毒治疗病例死亡的主要影响因素。方法采用AIDS综合防治数据信息系统中的HIV/AIDS死亡病例信息数据进行分析。结果对2010年1月-2011年7月死亡的5 265例有效个案进行分析,临床诊断为AIDS相关疾病死亡2 647例(50.3%),意外伤害410例(7.8%),其他疾病或难以确定与AIDS相关疾病的死亡1 973例(37.5%),不详235例(4.5%)。4 382例(83.2%)未接受抗病毒治疗的主要原因是,发现较晚(46.4%)和家庭经济困难(13.7%)。2004-2011年7月底,累计治疗AIDS病人21 761例,死亡1 718例。在有完整资料的1 694例死亡病例中,825例(48.7%)在治疗后3个月内死亡;1 065例(62.9%)治疗前最近1次检测CD4T淋巴细胞≤50个/μL。结论未能及时就医或诊断时间较晚,免疫功能低下,是HIV/AIDS病人死亡的主要影响因素。要进一步建立健全监测检测和治疗体系,提高覆盖面和可及性,争取HIV/AIDS病人早发现、早诊断,及时开展抗病毒治疗,降低病死率。
Objective To determine the causes of AIDS and non-AIDS related deaths among human immunodeficiency virus（HIV） and acquired immunodeficiency syndrome（AIDS）（HIV/AIDS） patients in Guangxi,and the impact factors associated with deaths of patients receiving highly active antiretroviral therapy（HAART）.Method Retrospective analysis was performed on the data of HIV/AIDS deaths derived from the HIV/AIDS Comprehensive Information System.Results As confirmed by clinical diagnosis,among the 5 265 HIV/AIDS deaths reported from January 2010 to July 2011,2 647（50.3%） cases died of HIV/AIDS,410（7.8%） cases died of injury,and 1 973（37.5%） cases died of other diseases or a disease that was uncertain to be related to AIDS.Unknown causes of death accounted for 4.4%（235） of the total deaths.The leading causes of death for 4 382（83.2%）patients not receiving free HAART were late diagnosis（46.4%） or being unaffordable to pay medical expenses（13.7%）.Between 2004 and the end of July of 2011 the accumulative treated AIDS cases amounted to 21 761,of whom 1 718 died.Of the 1 694 deaths with complete data,825（48.7%） died within the first 3 months after HAART was initiated.Of these deaths,1 065（62.9%） cases had CD＋4counts lower than 50 cell/μL in the last test before the initiation of HAART.Conclusion The leading causes of deaths among HIV/AIDS patients in Guangxi are AIDS and/or AIDS related diseases.The major risk factors related with the death are late diagnosis and low immunity.An integrated surveillance and treatment system should be established with expanded coverage and accessibility,and meanwhile efforts should be made to achieve early detection and diagnosis of AIDS patients and provide timely HAART so that AIDS mortality could be reduced.
出处
《中国艾滋病性病》
CAS
2013年第5期337-339,共3页
Chinese Journal of Aids & STD
