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Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin

Fluorescence quenching of triazatruxene-based glycocluster induced by peanut agglutinin lectin
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摘要 A novel triazatruxene-based fluorescent glycocluster was synthesized and its selective binding interactions with PNA lectin were investigated by fluorescence spectroscopy,CD spectroscopy,and a turbidity assay.The glycocluster exhibited a strong binding affinity for PNA lectin with a Stern-Volmer quenching constant of 5.8×10^5 mol^-1L A novel triazatruxene-based fluorescent glycocluster was synthesized and its selective binding interactions with PNA lectin were investigated by fluorescence spectroscopy,CD spectroscopy,and a turbidity assay.The glycocluster exhibited a strong binding affinity for PNA lectin with a Stern-Volmer quenching constant of 5.8×10^5 mol^-1L
作者 Ke-Rang Wang Hong-Wei An Dan Han Feng Qian Xiao-Liu Li
机构地区 Key Laboratory of Chemical Biology of Hebei Province Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2013年第6期467-470,共4页 中国化学快报（英文版）
基金 supported by the National Natural Science Foundation of China(Nos.21002020 and 21172051) the Hebei Natural Science Foundation(Nos.B2011201052 and B2012201041)
关键词 Triazatruxene Glycocluster Fluorescence quenching Peanut agglutinin Triazatruxene Glycocluster Fluorescence quenching Peanut agglutinin
分类号 O621.3 [理学—有机化学]
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Chinese Chemical Letters
2013年 第6期

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