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度洛西汀合并重复经颅磁刺激治疗老年抑郁症的对照研究 被引量:5

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摘要 目的分析度洛西汀合并重复经颅磁刺激治疗老年抑郁症的临床疗效。方法采用数字随机法将68例符合ICD-10抑郁发作诊断标准的老年抑郁症患者分为研究组和对照组各34例,研究组给予度洛西汀合并重复经颅磁刺激治疗,对照组给予度洛西汀合并伪刺激治疗,共6周。于治疗前及治疗1、2、4及6周末采用汉密尔顿抑郁量表评定临床疗效。结果治疗6周末,研究组和对照组总有效率分别为97.40%和78.10%,差异有统计学意义(P<0.05)。治疗前及治疗后1、2、4、6周末两组患者HAMD评分差异均有统计学意义(P<0.01),但两组间比较,差异则无统计学意义(P>0.05)。研究组发生不良反应25例(73.5%);对照组发生不良反应23例(67.6%),两组不良反应发生率差异无统计学意义(P>0.05)结论度洛西汀合并重复经颅磁刺激可提高老年抑郁症治疗的有效率。
作者 庞继松
机构地区 天津市安定医院
出处 《四川精神卫生》 2013年第2期118-119,共2页 Sichuan Mental Health
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