摘要
新生儿黄疸是全球儿科医生共同面对的难题,遗传因素在新生儿黄疸的发病中起重要作用。目前的研究认为,与新生儿黄疸发生有关的因素主要有G6PD、尿苷二磷酸葡萄糖醛酸转移酶1A1、编码有机阴离子转运体(OATP)的基因SLCO1B1和SLCO1B3,以及血红素加氧酶1和胆绿素还原酶A。
Neonatal jaundice is the problem that the world＇s pediatrician to face together. The genetic factors play an important role in the pathogenesis of neonatal jaundice. The current studies suggested that the major factors associated with neonatal jaundice including glucose-6-phosphate dehydrogenase deficiency （G6PD）, uridine diphosphate glucuronic transferase 1A1 （UGT1A1）, the SLCO1B1 and SLCO1B3 gene that encode the organic anion-transporting polypeptide （OATP）, heme oxygenase 1 and biliverdin reductase A.
出处
《分子诊断与治疗杂志》
2013年第3期206-210,共5页
Journal of Molecular Diagnostics and Therapy
