摘要
目的:观察右美托咪定应用于老年高血压患者椎管内麻醉镇静的效果及对血流动力学的影响。方法:将60例老年高血压患者随机分为右美托咪定组(D组)和对照组(C组),各30例。腰硬联合阻滞完成,D组静脉持续输注DEX,对照组同时输入等量生理盐水。观察并记录两组的血压、心率、呼吸频率、脉搏血氧饱和度(SpO2),同时监测Narcotrend指数(NTI)及镇静/警觉(OAA/S)评分。结果:两组患者的呼吸频率,心率和SpO2在组间比较差异无统计学意义。D组患者的血压稳定于平素时控制水平,与给药时及对照组相比差异有统计学意义(P<0.05);对照组患者血压全程均显著高于平素水平(P<0.05)。D组NTI和OAA/S评分与对照组相比差异有统计学意义(P<0.05)。全部患者术中无心动过缓发生。结论:右美托咪定应用于老年高血压患者椎管内麻醉期间镇静良好,能适度控制血压并保持血流动力学各项指标相对平稳。
Objective： To observe the dexmedetomidine applied to the sedative effects on elderly hypertensive patients with spinal anesthesia and the influence of hemodynamic.nethod： 60 elderly patients with hypertension were randomly divided into the dexmedetomidine given group （ D group ） and the control group （ C group ）, 30 patients in each group. With the completed epidural block, the D group was given intravenous continuous infusion of DEX and the control group was input the equivalent saline at the same time. Not only the blood pressure, heart rate, respiratory rate, SPO2 were observed, but also Narcotrend Index （ NTI ） and Observer＇ s Assessment of Alertness/Sedation （ OAA/S ） Score were simultaneously monitored during the operations. Result： Respiratory rate, heart rate and SPO2 showed no significant differences between the two groups, but the blood pressure of the Group D was more smoothly controlled after the beginning of administration and the level was significantly lower （ P〈0.05 ） than that in the control group whose pressure was substantially increasing during the whole operations, the NTI, the OAA / S score were statistically significant （ P〈0.05 ） in the Group D, compared with the control group that were without bradycardia. Conclusion： The elderly hypertensive patients with spinal anesthesia can be well-sedated by using Dexmedetomidine. Meanwhile, the blood pressure can be moderately controlled and the indicators of hemodynamic can be maintained stable as well.
出处
《中国医学创新》
CAS
2013年第16期28-30,共3页
Medical Innovation of China
关键词
老年
高血压
椎管内麻醉
右美托咪定
Elderly
Hypertensive patients
Spinal anesthesia
Dexmedetomidine
