摘要
目的探讨纳洛酮在高血压性脑出血治疗中的临床应用价值。方法采用前瞻性研究将80例高血压性脑出血患者随机分为研究组和对照组,分别给予不同的治疗,比较两组患者治疗效果及并发症发生情况。结果研究组的显效率和有效率分别为65%、90%,对照组分别为35%、65%;两组显效率和有效率经卡方检验后,χ2值分别为12.62、14.57,差异有统计学意义(P<0.05);研究组和对照组并发症发生率分别为12.5%、25%,经卡方检验后,χ2=13.68,差异有统计学意义(P<0.05)。结论纳洛酮能迅速地拮抗内源性阿片类物质,有效保护脑出血患者的脑组织,提高治疗疗效,降低并发症发生率,值得在临床上推广应用。
Objective To investigate the clinical value of naloxone in the treatment of hypertensive cerebral hemorrhage. Methods A prospective study, 80 patients with acute cerebral infarction were randomly divided into study group and control group,which were given a different treatment, the two groups were compared therapy and occurrence of complications. Results The research group efficiency and efficiency were 65%, 90%, and the control group were 35%, 65%; two groups significant efficiency and efficient after chi-square test, ~2 values were 12.62,14.57, the difference were statistically significant （P 〈 0.05）; Complication rate of the study group and the control group were 12.5% and 25%, respectively, after chi-square test, ~2 value of 13.68, the difference was statistically significant （P 〈 0.05 ）. Conclusion Naloxone can quickly antagonize endogenous opioids, the effective protection of the brain tissue of cerebral hemorrhage patients, improve the therapeutic efficacy, reduce the incidence of complications, and it is worthy of clinical application.
出处
《中国现代医生》
2013年第16期60-61,共2页
China Modern Doctor
关键词
纳洛酮
高血压
脑出血
Naloxone
Hypertension
Cerebral hemorrhage
