摘要
目的 探讨心理应激对腺垂体促甲状腺素细胞的影响。方法 采用心理应激模型 ,并在不同应激条件下对大鼠腺垂体促甲状腺素细胞进行免疫组织化学和电镜观察 ,并用体视学公式作定量分析。结果 应激大鼠促甲状腺素细胞体积密度 (Vv)和数密度 (Nv)的值均低于正常对照组 ,且在不同应激条件的A、B、C三组存在显著差别。结论 心理应激可不同程度地抑制大鼠腺垂体促甲状腺素细胞合成和分泌促甲状腺素。
Objective In order to study the effects of psychological stress on the thyrotrophin cell of pituitary.Methods Immunohistochemical techniques ,quantitative sterological analysis and electromicroscopy was used to examine the changes of thyrotrophin cell in pituitary in the psychological stressed rats.Results The volume density and numerical density of thyrotrophin cell of pituitary in the psychological stressed rats were lower than that in the normal groups,and the three psychological stressed groups different from each ofther in volume density and numerical density.Conclusion The synthesis and secretion of thyrotrophin of pituitary in rats may be inhibited by psychological stress.
出处
《解剖学研究》
CAS
2000年第1期19-21,共3页
Anatomy Research
基金
国家自然科学基金 (No:396 6 0 0 2 5 )
广西科学基金资助
关键词
心理应激
促甲状腺素
垂体
大鼠
定量分析
Psychological stress
Pituitary
Thyrotrophin
Rat
Quantitative analysis
