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N端脑利钠肽前体在急性心力衰竭治疗中的价值 被引量:9

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摘要 目的:探讨N端血浆脑利钠肽前体(NT-proBNP)在急性心力衰竭临床治疗中的价值。方法:用免疫荧光法测定60例急性心力衰竭患者(AHF组)及60例同期住院诊断为肺部感染的患者(对照组)血浆NT-proBNP浓度;超声心动图测定左室射血分数(LVEF)。比较两组治疗前后血浆NT-proBNP浓度、LVEF的变化。结果:AHF组NT-proBNP值明显高于对照组,差异有统计学意义(P<0.01),且AHF组血浆BNP水平随NYHA分级增高而升高;亚组分析显示,心功能Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级各组间比较,BNP水平差异均有统计学意义(P<0.01);治疗后1周NT-proBNP值同治疗前有显著降低(P<0.01)。结论:监测NT-proBNP浓度对急性心力衰竭的治疗具有指导作用。
作者 章雄军
机构地区 河源市人民医院
出处 《赣南医学院学报》 2013年第2期231-232,共2页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
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参考文献5

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共引文献14

同被引文献95

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