摘要
为探讨猪血红蛋白脂质体输给猫的可能性,通过制备猪血红蛋白脂质体后,经过股内侧静脉输入到猫的体内,检测输血前后猫的临床指标变化及其输血前后血常规和尿常规指标。观察异源输入猪源血红蛋白脂质体对猫机体的影响,以及检测猫异源输入血红蛋白脂质体的可行性。结果输血后未有明显的临床异常反应和输血反应。提示猪血红蛋白脂质体用于猫输血的可能,表明猪血红蛋白脂质体是一种新型的安全的血液代用品。
Abstraet.The possibility of porcine hemoglobin liposome infused to cat was studied. The porcine hemoglo- bin liposome was prepared and infused to cat through medial femoral vein. The clinical indicators of cat were observed, and blood and urine routine indexes were detected before and after blood transfusion. The effect of heterologous infusion of porcine hemoglobin liposome on cat was observed as well as the feasibility of heterologous infusion was detected. The cat had no obvious clinical abnormal reaction and blood transfu- sion reaction after transfusion. It is possible to infuse porcine hemoglobin liposome to cats. It implies that porcine hemoglobin liposome is a novel and safe blood substitutes. Key words： porcine hemoglobin; cat ; liposome ; blood transfusion
出处
《动物医学进展》
CSCD
北大核心
2013年第5期125-128,共4页
Progress In Veterinary Medicine
基金
湖南省2011年研究生科研创新项目(CX2011B273)
湖南省大学生研究性学习和创新性实验计划项目(SCX1113)
湖南农业大学大学生创新项目(XCX1145)
关键词
猪血红蛋白
猫
脂质体
输血
porcine hemoglobin
cat
liposome
blood transfusion
