摘要
目的:研究云南鸡屎藤根、茎、叶水提取物的体外抑菌、杀菌作用。方法:采用常量稀释法测定云南鸡屎藤根、茎、叶水提取物分别对金黄色葡萄球菌、痢疾杆菌、大肠杆菌、绿脓杆菌的体外抑菌、杀菌作用。结果:云南鸡屎藤根、茎、叶对4种供试菌均有抑菌、杀菌作用,其中根对绿脓杆菌的抑菌、杀菌作用最强,对4种供试菌的抑菌、杀菌作用在3个实验药中均最优。叶对痢疾杆菌的抑菌作用最强,对金黄色葡萄球菌的杀菌作用最强。结论:云南鸡屎藤根、茎、叶水提取物对4种供试菌都有抑菌、杀菌作用,但存在明显差异,为下一步中药抗菌的标准化提供基础。
Objective： To study the bacteriostatic and bactericidal effects in vitro of aqueous extract of Paederia yunnanensis. Methods： Solution dilution method is used to measure the bacteriostatic and bactericidal effects of roots, stems and leaves of Paederia yunnanensis against Staphylococcus aureus, Shigella dysenteriae, Escherichia coli, and Pseudomonas aeruginosa. Results： All of three parts have bacteriostatic and bactericidal effects on the four experimental bacteria, but there are also significant differences. The root of Paederia yunnanensis has the strongest bacteriostatic and bactericidal action against Pseudomonas aeruginosa, and it is also the part with the best bacteriostatic and bactericidal effect for four experimental bacteria as a whole. The leaves of Paederia yunnanensis have the strongest bacteriostatic action against Shigella dysenteriae, and the stongest bactericidal action against Staphylococcus aureus. Conclusion： The roots, stems, and leaves of Paederia yunnanensis have bacteriostatic and bactericidal actions against four experimental baceria, but also there are differences among their effects, and to provide the basis for the next step of antibacterial medicine standardization.
基金
大理学院青年教师科研基金资助项目(KYQN2010-58)
关键词
云南鸡屎藤
水提取物
体外抗菌
Paederia yunnanensis
water extract
research in vitro
