摘要
目的 分析深圳地区居民糖尿病危险因子与Ⅱ型糖尿病发病的关系。方法 采用WHO诊断标准 ,随机抽样 8182人 ,进行问卷调查、体格检查、血液生化指标测定 ,用logistic多元回归分析糖尿病危险因子。结果 血清总胆固醇高于正常值范围人群的Ⅱ型糖尿病患病率为 12 46 % ,是正常人群的 4 9倍。甘油三酯高于正常值范围人群的Ⅱ型糖尿病患病率为 12 6 0 % ,是正常人群的 5 7倍。高密度脂蛋白低于正常值范围人群的Ⅱ型糖尿病患病率为 6 5 9% ,比正常者升高 6 8 7% ;而高密度脂蛋白值高于正常值范围人群的Ⅱ型糖尿病患病率仅为 2 17% ,比正常者降低 44 6 %。体块指数≥ 2 5人群的Ⅱ型糖尿病患病率达 8 0 6 % ,是体块指数 <2 5人群的 2 6倍。腰 /臀比值≥ 1 0的人群Ⅱ型糖尿病患病率高达 19 89% ,是 <1 0人群的 5 1倍。高血压患者Ⅱ型糖尿病患病率高达12 48% ,是非高血压者的 3 8倍。Ⅱ型糖尿病患病率随年龄的增长呈上升趋势 ,尤以 40岁以后人群更为明显。有糖尿病家族史者、分娩巨大婴儿 (≥ 4kg)史的妇女 ,Ⅱ型糖尿病患病率明显增加。随着吸烟和 /或饮酒量的增加以及年限的延长 ,Ⅱ型糖尿病患病率明显升高。结论 血清总胆固醇、甘油三酯与血糖呈正相关 ,高密度脂蛋白胆固醇与血糖呈负相关。总胆固醇?
Objective The study was designed to investigate the risk factors of Type 2 diabetes in the new city Shenzhen. Methods A representative sample of 8 182 adults aged over 20 to 75 years old were randomly selected in the residents of Shenzhen, China in 1997. Type 2 diabetes was diagnosed according to the WHO criteria. Questionnaire survey, anthropometric measurement and blood analysis were carried out, and logistic regression analysis was used to study the risk factors. Results The results showed that the prevalence of type 2 diabetes in subjects with high total cholesterol were 49 times of those with lower TC value. Subjects with high triglyceride had a prevalence 57 times of those who had lower TG. Those HDL-ch had a prevalence 687% higher than those with normal HDL-ch value; on the other hand, those HDL-ch >191 mmol/L were 446% lower in the prevalence than those with normal HDL-ch. The prevalence of type 2 diabetes in subjects with BMI ≥25 were 26 times of those with BMI <25 Subject with hypertension (≥140/90 mm Hg) had a prevalence 38 times of those with normal blood pressure. Subjects with family history of type II diabetes had a prevalence 20 times of no family history, and women who had delivered babies over 4 kg had a prevalence 19 times of those who had babies less than 4 kg. Subjects with waist/hip ratio (WHR) ≥10 had a prevalence 51 times of those with WHR <10. The prevalence of type 2 Diabetes was higher with increasing amount of cigarette smoking and the duration (in years) of smoking or increasing drinking (alcohol) and the duration (in years) of drinking. Conclusions The blood glucose level was found to be positively correlated with TC or TG, and negatively correlated with HDL-ch. This study demonstrated again that TC, TG, HDL-ch, obesity, hypertension, family history of type 2 diabetes and in women, delivery of babies over 4 kg and age were risk factors of type 2 diabetes.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2000年第4期232-234,共3页
Chinese Journal of Preventive Medicine
关键词
Ⅱ型糖尿病
危险因素
胆固醇
甘油三酯
脂蛋白
Diabetes mellitus, non-insulin-dependent
Risk factors
Cholesterol
Triglycerides
Lipoproteins, HDL
