摘要
肿瘤的转移与复发已成为影响癌症患者治疗疗效和获得长期生存的关键因素，也是当前肿瘤临床研究的热点。蛋白质组学在恶性肿瘤与正常组织之间表达存在差异，可用作筛选肝癌新的肿瘤标志物。临床上通过对肝癌相关的蛋白质分子进行检测，可以对肝细胞癌早期的诊断、复发及预后进行监测和评估。本文就肝细胞癌相关蛋白质分子的研究进展作一综述。
Tumor metastasis and recurrence had become a key to curative etIect and long-term survival, and it＇s hotspot of cun＇ent clinical oneology research. Differential expression of proteomics between cancer and normal tissue can be used for discovering new tumor markers. Clinical detection of liver cancer-related protein molecules was use- fill to monitor and assess early diagnosis, recurrence and prognosis of hepatocellular eareinoma. Herein, this article reviewed the research progression of protein molecules in hepatocellular carcinoma.
出处
《国际外科学杂志》
2013年第5期322-327,共6页
International Journal of Surgery
基金
国家自然科学基金资助项目（No.81172364）
安徽高校省级一然科学研究重点项目（No.KJ2011A171）
安徽省科技攻关项目（No.12010402112）
关键词
肝肿瘤
蛋白质组学
生物学标志记
肿瘤转移
复发
Liver neoplasms
Proteomics
Biological markers
Neoplasm metastasis
Recun＇enee
