摘要
目的探讨性腺母细胞瘤的临床病理特点、鉴别诊断及治疗与预后。方法对2例性腺母细胞瘤的临床资料、病理形态进行分析。结果 2例患者体表特征均为女性,主要症状为无月经来潮,检查发现性腺发育不良。例1肿块直径0.4 cm,例2为1.0 cm×0.8 cm×0.5 cm大小。光镜下性腺母细胞瘤由两种细胞构成,大的生殖细胞周围散在小的性索细胞,其周边可见大量无定形的透明Call-Exner小体样结构围绕,可见散在钙化点。结论性腺母细胞瘤具有特定的临床和组织学特征,但合并其他生殖细胞肿瘤时容易漏诊,也可能误诊为其他生殖细胞肿瘤而治疗不当。
Objective To analyze the clinical features, differential diagnosis, therapy and prognosis of gonadoblastoma. Methods In this study, two cases of gonado blastoma were analysed about clinical data and histopathol0gy. Results Both of them were female phenotypic. The main symptom of this disease was amenorrhoea and gonadal dysgenesis. The sizes of the tumors were 0. 4 cm in diameter and 1.0 cm × 0. 8 cm× 0. 5 cm, respectively. Histological examination showed that gonadoblastoma was consisted of two cell types ： large germ cells surrounded by small cells of sexual cords. These cells were frequently arranged surrounding small round deposits containing amorphous hyaline material resembling Call-Exner bodies. Calcific foci distributed in all areas of the tumors. Conclusions Gonadoblastoma has specific clinical and histological features, but the improper therapy will be resulted if it is associated with or misdiagnosed as other germ cell tumors.
出处
《诊断病理学杂志》
CSCD
北大核心
2013年第5期279-281,285,共4页
Chinese Journal of Diagnostic Pathology
关键词
性腺母细胞瘤
临床病理诊断
鉴别诊断
Ganadoblastoma
Clinical pathological diagnosis
Differential diagnosis
